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San Francisco 49ers head coach Kyle Shanahan speaks with quarterback Jimmy Garoppolo between plays against the Jacksonville Jaguars during the second quarter at Levi’s Stadium.

All the NFL odds info you need to get ready for Week 5

Week 5 of the 2019 NFL season is upon us. We’ll break down all the pertinent injury and odds news to get you ready for your betting decisions in Week 5.

Contributors: DraftKings Nation Staff

The NFL is through the quarter mark, and we still don’t know quite who all the best teams are in 2019. The undefeated New England Patriots and Kansas City Chiefs are clearly contenders, but what about the also unbeaten San Francisco 49ers? Week 5 brings a big matchup for the 49ers at home against the Cleveland Browns on Monday Night Football, so maybe we get an answer there.

As Week 5 moves along, there is plenty of information to consider in deciding how we want to wager on various games. We’re not going to bet on every single matchup on the card, but there are some intriguing ones. Our decisions will be influenced by injury news and depth chart changes, so we’re here to help you prepare for everything that will go down this week.

Check back for news updates as well as analysis and picks. We’ll have an odds rundown for each game and best bets to sufficiently prep you. Good luck with your wagering in Week 5!

27 Total Updates Since
Sep 29, 2019, 5:51pm PDT

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October 7, 2019
Point spread, total, moneyline and more for Browns-49ers on Week 5 MNF [UPDATE]

By mitchelllapierre

The 49ers look to remain unbeaten while the Browns look to stay atop the AFC North. We break down notable odds, including the point spread, prop bets and ATS history.
October 6, 2019
Best bets for Week 5 of the NFL season

By Julian Edlow

A breakdown of spots to consider targeting and fading on the Week 5 NFL betting card
October 6, 2019
Point spread, total, moneyline and more for Bills-Titans in Week 5

By Alex Rikleen

The Bills and Titans are in the playoff hunt early and look to stay on a winning path. We break down notable odds, including the point spread, prop bets and ATS history.
October 6, 2019
Best NFL Survivor pool options for Week 5

By David Fucillo@davidfucillo

It’s time to unveil my Week 5 strategy in a pair of NFL Survivor pools.
October 6, 2019
Point spread, total, moneyline and more for Bucs-Saints in Week 5

By Anthony Amico

Everything you need to know heading into this NFC South showdown.
October 6, 2019
Point spread, total, moneyline and more for Colts-Chiefs in Week 5 SNF

By Alex Rikleen

We get a fun one for Week 5 Sunday Night Football. The Colts get a huge test in the high flying Chiefs. We break down key odds, including the point spread, notable prop bets, and important trends.
October 6, 2019
Point spread, total, moneyline and more for Packers-Cowboys Week 5

By Alex Rikleen

The Cowboys and Packers square off in a huge matchup of NFC division leaders. We break down the key odds, including the point spread, notable prop bets, and ATS history.
October 6, 2019
Spread picks for every NFL game in Week 5

By David Fucillo@davidfucillo

It was a brutal Week 4 for me, so it’s time to bounce back. Here’s my full picks, including some best bets.
October 5, 2019
Top 25 TE standard options for Week 5 fantasy football

By Derek Gordon

We break down the tight ends to consider as Week 5 is upon us.
October 5, 2019
The best underdogs to bet in Week 5

By mikebarner

We’re going with shaky squads as our best bets for Week 5. We’ve got two young quarterbacks and a veteran to keep things interesting on Sunday.
October 5, 2019
Point spread, total, money line and more for Falcons-Texans in Week 5

By mitchelllapierre

The Falcons stink and their pass defense could be super inviting for the Texans. Maybe bet the over? We take a look at key odds including the point total, spread, betting history, and more.
October 5, 2019
Point spread, total, moneyline and more for Jets-Eagles in Week 5

By Anthony Amico

The Jets are just trying to survive without former first round pick Sam Darnold, and now they get the Eagles coming off a big Week 4 win. We break down notable odds, including the point spread, prop bets, and ATS history.
October 5, 2019
Point spread, total, moneyline and more for Ravens-Steelers in Week 5

By mitchelllapierre

The AFC North is officially wide open after a wild Week 4. Long time rivals Baltimore and Pittsburgh square off looking to get an edge. We break down key odds, including the point spread, prop bets, ATS history, and more.
October 5, 2019
Point spread, total, moneyline and more for Cardinals-Bengals in Week 5

By mitchelllapierre

The Cardinals look to get their first win against winless Cincinnati. We break down the key Week 5 odds, including the point spread, prop bets, and more.
October 4, 2019
Josh Allen remains in concussion protocol at end of Week 5 practice

By David Fucillo@davidfucillo

Buffalo Bills quarterback Josh Allen is in the concussion protocol and his status for Week 5 is uncertain. We break down the fantasy and gambling implications.
October 4, 2019
Point spread, total, money line and more for Patriots-Washington in Week 5

By Alex Rikleen

The Patriots are huge favorites heading into the nation’s capital. They face a Washington team with questions at quarterback, among other areas. We break down the huge point spread, and more odds.
October 4, 2019
Point spread, total, moneyline and more for Jaguars-Panthers in Week 5

By Alex Rikleen

Gardner Minshew takes his show on the road as the Jaguars travel to face the Panthers. We break down key odds, including ATS history, the point spread, and notable prop bets.
October 4, 2019
Point spread, total, moneyline and more for Vikings vs. Giants in Week 5

By Anthony Amico

Daniel Jones looks to win his third straight as the Giants face the tough Vikings defense. We break down the key odds, including the point spread, prop bets, and recent betting history.
October 4, 2019
Point spread, total, moneyline and more for Broncos-Chargers in Week 5

By Anthony Amico

Melvin Gordon is set to make his on-field return in Week 5 as the Chargers host the Broncos. We break down notable odds, including the point spread, ATS history, and prop bets.
October 3, 2019
Laying the points at home in the NFC West

By David Fucillo@davidfucillo

The Seahawks and Rams square off in Week 5 Thursday Night Football. I’m a fan of the home team in this one.
October 1, 2019
Josh Allen remains in concussion protocol heading into Week 5

By David Fucillo@davidfucillo

Bills quarterback Josh Allen suffered a concussion in Week 4. We break down the fantasy implications as Buffalo prepares for Week 5 vs. Tennessee.
October 1, 2019
James Conner being evaluated for ankle injury after Week 4 win

By David Fucillo@davidfucillo

Steelers running back James Conner injured his ankle in the team’s Week 4 win over the Bengals. We break down the fantasy implications for Week 5.
October 1, 2019
3 teams that improved SB54 odds the most heading into Week 5

By mitchelllapierre

Week 4 is a wrap, which means we have a new look at Super Bowl 54 futures odds. We break down three teams of note rising up the leaderboard.
October 1, 2019
Tevin Coleman looking better coming off Week 4 bye

By David Fucillo@davidfucillo

49ers running back Tevin Coleman is working back from a high ankle sprain. We break down the fantasy implications of news heading into Week 5 off a bye.
October 1, 2019
Christian Kirk dealing with ankle injury heading into Week 5

By David Fucillo@davidfucillo

Cardinals wide receiver Christian Kirk came up with an unexpected injury in Week 4. We break down the fantasy football implications heading into a great Week 5 matchup.

All the NFL odds info you need to get ready for Week 5

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