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Best lineup strategy for 49ers-Seahawks in MNF FanDuel Showdown

Monday Night Football pits two of the top teams in the NFL against each other. We try to pick out the best plays for the DFS single game showdown.

San Francisco 49ers wide receiver Emmanuel Sanders celebrates a first quarter first down against the Arizona Cardinals at State Farm Stadium. Mark J. Rebilas-USA TODAY Sports

UPDATE: The 49ers have activated tight end Garrett Celek off injured reserve for Week 10 vs. the Seattle Seahawks. This would suggest that George Kittle will be inactive for the game due to his knee injury. Ross Dwelley is likely to get the start in place of Kittle.

Tonight brings an end to Week 10 of the NFL season, as the 49ers host the Seahawks. This game has plenty of real-life repercussions for the NFL and especially the NFC West, but there is also a load of fantasy players to choose from for a single-game slate on FanDuel.

Monday Night Football currently has an over/under set at 47.5, and the undefeated 49ers favored by -6. If the odds prove close to the outcome, we should see Russell Wilson given the keys to the Tesla and the 49ers running the ball often.

Injuries

The most significant injury tonight is to George Kittle, who is doubtful with a knee injury. Ross Dwelley should see the most significant increase in work, but Levine Toilolo will also see some action.

Kicker Robbie Gould is doubtful and will be replaced by Chase McLaughlin.

San Francisco also gets offensive linemen Joe Staley and possibly Mike McGlinchey back to shore up the line. Fullback Kyle Juszczyk should also return, giving the running game an extra boost.

Seahawks’ new wide receiver Josh Gordon is a game-time decision, but Pete Carroll said that there is a good chance he will play.

Opportunity

49ers

Over the last two weeks, Matt Breida has out-touched Tevin Coleman 29 to 27, but Coleman has six targets to Breida’s three in that span.

Kittle’s absence opens up seven targets per game. Emmanuel Sanders and Deebo Samuel have the most targets after Kittle and look to see a bump, but Marquise Goodwin was a healthy scratch last week due to missing practice for a personal matter. He could return and pass Samuel again in work, but that’s a tough call to make.

Seahawks

Chris Carson remains a steady workhorse with 22 touches per game.

Tyler Lockett and DK Metcalf have been the only receivers to see enough work for fantasy production as receivers, and now Josh Gordon joins the group. Gordon is likely to be eased in for his first game if he plays, but he could cut into Metcalf’s workload if they try to get him involved this week.

Ed Dickson, Luke Willson, and Jacob Hollister will all get run this week. Hollister scored two touchdowns on six targets last week, so should remain the No. 1 tight end target.

Core Plays and Captains Chair

In team defense DVOA, the 49ers rank first against the pass and 20th against the run while Seattle ranks 21st against the pass and 22nd against the run.

I think we can safely say the Seahawks defense is worse than the 49ers overall, but we did see Kenyan Drake put it to the 49ers run defense last week, and Chris Carson is even more equipped than Drake to take advantage. Seattle will get Carson the ball even when trailing, but of course, we’d rather him have a lead to work with.

Russell Wilson gets his toughest matchup of the season, as the 49ers have allowed the fewest fantasy points to quarterbacks. Still, they’ve also played a relatively weak QB schedule, with Kyler Murray, the best quarterback they’ve faced. Murray also had the best game against them with 241 yards passing, two touchdowns, and 34 yards rushing with no turnovers. We know what Wilson can do, and I don’t think the 49ers defense will contain him all game. And if you’re putting Wilson in the captain’s chair, you will have a hard time not putting Tyler Lockett in your lineup.

Looking for a captain from the 49ers is tough due to their propensity to spread the ball around, but with George Kittle out, Emmanuel Sanders has a chance to see enough work funneled his way to feel good about his fantasy floor.

Jimmy Garoppolo’s Week 10 was eye-opening, as he didn’t just put it on a weak Cardinals defense, he made throws that would have beaten any defense. The main worry for Garoppolo this week is the absence of Kittle and a lowered workload if the run game is clicking, especially with Staley and Juszczyk back. But if Wilson can get a lead, Garoppolo has proven he has the ability to put up good fantasy points.

One of Tevin Coleman or Matt Breida has a good shot at taking the captain’s chair, but their production fluctuates between the two. I do like the 49ers run game this week though, so I can see diversifying your lineups by using both in multiple lineups.

Captains: Russell Wilson ($16,000), Emmanuel Sanders ($11,500)

Core Players: Chris Carson ($12,000), Tyler Lockett ($13,500), Matt Breida (9,000). Tevin Coleman ($11,000), Jimmy Garoppolo ($15,000)

Value Plays

Matt Breida is a core play, but also a value play at just $9,000 after out-touching Coleman the last two weeks. His price makes him a tough player to fade.

Deebo Samuel has home run ability and a friendly price of $8,000. If Marquise Goodwin doesn’t play, then Samuel is a strong play after seeing ten targets the last two games with Goodwin out.

Josh Gordon has upside based on the team possibly wanting to get him involved quickly, and his price is dirt cheap at $7,000. He’s not safe, and he may not even suit up, but if he does, the upside is there.

Marquise Goodwin was starting before he missed the last two games with a personal issue, so if he returns this week, he should have great value at $6,000 with Kittle out.

Ross Dwelley had four targets with Kittle nursing his knee injury last week, and he caught all four for 29 yards. At $5,000, he could help you put together a scrubs and studs lineup.

Jason Meyers isn’t super cheap at $9,500, but he has put up good numbers with an average of 10 FanDuel points in his last three. It would be nice if Chase McLaughlin, Robbie Gould’s replacement, were in this contest, but he was signed too late.

Value Plays: Matt Breida ($9,000), Marquise Goodwin ($6,000) or Deebo Samuel ($8,000). Ross Dwelley ($5,000)