George Kittle and Matt Breida INACTIVE for Week 11

After both San Francisco 49ers TE George Kittle (ankle/knee) and RB Matt Breida (ankle) were listed as doubtful, both have been ruled INACTIVE for today’s matchup vs. the Arizona Cardinals. The news isn’t all that surprising, though Kittle did recently say he felt “fantastic” and on track to return in Week 12. Breida left in the second half of last week’s loss to the Seahawks and did not return. It was initially reported that Breida would miss 1-2 weeks, per ESPN’s Adam Schefter, so again, he was supposed to be sidelined.

Fantasy Football Analysis: 49ers offense

No Breida and Kittle obviously hurts San Fran’s offense quite a bit. Kittle is one of the top pass-catching TEs in the NFL and a very good blocker in the run game. That run game loses versatility with Breida out, but the position is deep for the 49ers. Tevin Coleman ($6,100 on DraftKings) is in a strong spot vs. Arizona, which allows 126 rushing yards per game, ninth-worst in the NFL. Raheem Mostert ($3,400) is questionable but expected to play, and will eat into some of Coleman’s touches and targets, but not a significant amount. Coleman is a must-start in all formats.

With Kittle sidelined, the 49ers have used Ross Dwelley ($3,400) as the featured TE, playing on 80-of-88 offensive snaps in Week 10 vs. Seattle. Dwelley received seven targets, hauling in three catches for 24 yards in that game, but has the premier matchup for TEs on the slate. The Cardinals allow the second-most receiving yards per game at 286.5 and have allowed 28 or more points in each of their past three games. Kittle posted a 6-79-1 line vs. Arizona a few weeks ago, so at this price, Dwelley is the chalk TE in my mind on DK. He’s also an appealing streamer in shallow leagues and if you have Kittle, you should have picked up Dwelley.