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Opening point spreads for Week 12 NFL action

Week 12 brings a massive NFC matchup, and some critical AFC contests. We’ve got all the opening point spreads as they arrive.

Super Bowl 50 Proposition Bets At The Westgate Las Vegas Race & Sports SuperBook Photo by Ethan Miller/Getty Images

The NFL is wrapping up Week 11, with the Rams hosting the Bears on Sunday Night Football as of this publishing. The week wraps up on Monday with a huge AFC West showdown on Monday Night Football between the Chiefs and Chargers in Mexico City. In the meantime, opening lines are starting to arrive for Week 12.

The week opens with a monster AFC South matchup on Thursday Night Football. The Texans host the Colts with the two teams tied at 6-4. DeShaun Watson had one of the worst games of his career in a Week 11 loss to the Ravens, while the Colts welcomed back Jacoby Brissett and lost Marlon Mack to a broken hand in their win over the Jaguars.

The Saints are 9.5-point favorites in their divisional showdown with the Panthers. If New Orleans wins, it effectively locks up the division. Meanwhile, the Patriots get their second straight NFC East matchup, this time hosting Dak Prescott and the Cowboys. Considering how good the Patriots pass defense has been, it’s a huge test for the Cowboys passing game. Sunday wraps up with a titanic matchup between the Packers and 49ers on Sunday Night Football. The winner will have the best record in the NFC heading into Thanksgiving.

We’ll have plenty more on the point spreads for Week 12, but in the meantime, here is what the opening lines are looking like at DraftKings Sportsbook, with the point total in parenthesis next to the favorite). The Rams-Ravens Monday Night Football line is not available yet. The four teams on bye this week are the Chiefs, Vikings, Cardinals, and Chargers.

Indianapolis Colts @ Houston Texans (-3.5, 46.5)
Carolina Panthers @ New Orleans Saints (-9.5, 48)
Denver Broncos @ Buffalo Bills (-5, 36.5)
Detroit Lions @ Washington (+2.5, 41.5)
Miami Dolphins @ Cleveland Browns (-11, 44.5)
New York Giants @ Chicago Bears (-7, 41)
Oakland Raiders @ New York Jets (+3.5, 47)
Pittsburgh Steelers @ Cincinnati Bengals (+6, 39.5)
Seattle Seahawks @ Philadelphia Eagles (-2.5, 49)
Tampa Bay Buccaneers @ Atlanta Falcons (-4, 53)
Jacksonville Jaguars @ Tennessee Titans (-3, 41.5)
Dallas Cowboys @ New England Patriots (-6.5, 46)
Green Bay Packers @ San Francisco 49ers (-3, 45.5)