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Opening point spreads for Week 10 NFL action

Week 10 brings a huge Monday Night Football contest, and some big games for early playoff positioning. We’ve got all the opening point spreads as they arrive.

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The NFL is wrapping up Week 9, with the Ravens hosting the Patriots on Sunday Night Football as of this publishing. We get an NFC East matchup between the Dallas Cowboys and New York Giants on Monday Night Football that could be a fun one. In the meantime, opening lines are starting to arrive for Week 9.

The 49ers remained undefeated following a close Thursday Night Football win over the Cardinals. They host the Seahawks in Week 10 on Monday Night Football, and have opened as a 6.5-point favorites. This marks the first time since 2014 that the 49ers have been favored over the Seahawks.

The Patriots entered Week 9 undefeated, but are currently playing the Baltimore Ravens on Sunday Night Football. Lamar Jackson is off to a solid start, but there is a long way to go in that game. The Patriots are on bye in Week 10.

The biggest early lines are Saints -12 vs. the Falcons and Colts -11.5 vs. the Dolphins. The Colts line is of particular note because we don’t know the status of quarterback Jacoby Brissett for the game. He sprained his knee in Week 9 and will undergo an MRI.

An intriguing one has to be the Packers as 5.5-point home favorites over the Panthers. Carolina bounced back from an ugly Week 8 to get a big win over Tennessee in Week 9. On the other side of things, Packers struggled mightily against the Chargers. One has to wonder what the line might have been with a better showing from Green Bay.

We’ll have plenty more on the point spreads for Week 10, but in the meantime, here is what the opening lines are looking like at DraftKings Sportsbook, with the point total in parenthesis next to the favorite). We do not have the Vikings-Cowboys line yet while awaiting the result of Week 9 MNF. The four teams on bye this week are the Broncos, Eagles, Jaguars, Patriots, Texans, and Washington.

Los Angeles Chargers @ Oakland Raiders (-1.5, 47)
Arizona Cardinals @ Tampa Bay Buccaneers (-5, 53.5)
Atlanta Falcons @ New Orleans Saints (-12, 51)
Buffalo Bills @ Cleveland Browns (-2.5, 41.5)
Detroit Lions @ Chicago Bears (-3.5, 43.5)
Miami Dolphins @ Indianapolis Colts (-11.5, 43)
Carolina Panthers @ Green Bay Packers (-5.5, 48)
Los Angeles Rams @ Pittsburgh Steelers (+4, 45)
Seattle Seahawks @ San Francisco 49ers (-6.5, 44.5)