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Ten best players available on Week 16 waivers

We break down the 10 best fantasy football options on the waiver wire heading into Week 16.

Minnesota Vikings running back Mike Boone in action against the Oakland Raiders at U.S. Bank Stadium.  Jeffrey Becker-USA TODAY Sports

There’s one game left in the fantasy season and we may actually have a pickup or two this week that could move the odds in your favor for your league’s championship. Or, at least help keep your opponent from boosting their odds.

There were some big games from unexpected players this week and some big names went down with injuries, opening up work for some strong waiver wire adds.

Mike Boone (0.1 percent), Alexander Mattison (30.4 percent), RB, Vikings

Dalvin Cook hurt his shoulder and was immediately ruled out against the Chargers, which gave Mike Boone a chance to work with Alexander Mattison out as well. Boone rushed 13 times for 53 yards and two touchdowns as the Vikings walloped the Chargers. Next week they get a poor Packers run defense and whoever gets the start should be a good fantasy play, as all three of the Vikings running backs are good. Mattison thought he would be able to play early last week but wasn’t able to practice. Cook’s injury is an unknown as of this writing but it appears to be an aggravation of his shoulder injury. I doubt the team will push him unless he’s feeling better soon.

Breshad Perriman, WR Buccaneers (7.4 percent)

With Chris Godwin likely out and Mike Evans on I.R., Breshad Perriman is a must pickup after catching three touchdowns against the Lions. Scotty Miller also went down with a hamstring injury, so targets are going to funnel even more toward Perriman, likely making him a high upside and safe play in the highest over/under game of Week 16 against the Texans.

Anthony Miller, WR, Bears (24.2 percent)

Anthony Miller has stepped up of late and is coming off his best game of the season against the Packers. He now has a touchdown in his last two games and two nine reception, 100+ yard games in his last three. Kansas City isn’t a great spot next week but the Bears will likely be throwing the ball a bunch.

Tyler Higbee, TE, Rams (28.1 percent)

Higbee continues to play ahead of Cooper Kupp and has now topped 107 yards in each of his last three games and he’s been especially good in PPR, as he has 26 receptions on 33 targets in that span. The 49ers aren’t going to be easy next week, but he is getting too much work to ignore.

Danny Amendola, WR, Lions (16.2 percent)

With Marvin Jones out, Amendola picked up a big chunk of targets as he caught 8-of-13 for 102 yards against the Buccaneers. Denver is a tougher matchup but Chris Harris will shadow Kenny Golladay and Amendola could be a strong target once again.

Greg Ward, WR, Eagles (1.3 percent)

Ward stepped up with Alshon Jeffery and Nelson Agholor out, catching 7-of-9 targets for 61 yards and a touchdown against Washington. That gives him nine targets in each of his last two games and this week he faces the Cowboys in a must win game. As long as Agholor is out again, Ward has plenty of value.

O.J. Howard, TE, Buccaneers (51.4 percent)

Howard saw eight targets with Evans out and should see even higher usage with slot receiver Chris Godwin out against the Texans in Week 16.

N’Keal Harry, WR, Patriots (8.9 percent)

With Julian Edelman banged up, the Patriots tried getting the ball to Harry, as they gave him two carries and four targets. He turned those into 37 yards and a touchdown. With so few options at receiver right now, Harry looks like the best option after Edelman.

Jonnu Smith, TE, Titans (7 percent)

The Titans want to get Smith the ball and that showed this week when they gave him a carry which he took for 57 yards. He also caught all five of his targets for 60 yards and faces a Saints team next week that has had trouble with tight ends of late.

Boston Scott, RB, Eagles (2.5 percent)

Miles Sanders went off against Washington in Week 15 but Scott was his backup and a pass-catching back, as he rushed six times for 26 yards and caught seven passes for 39 yards. He’s now had six and seven receptions in his last two games and will likely have similar usage against Dallas in Week 16.