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Point spread, total, money line, injury report and more for Cardinals-Seahawks in Week 16

Kenyan Drake and Chris Carson are fresh off of huge weeks, but the passing games should prevail this time around. We break down notable odds, including the point spread, trends, and ATS history.

Arizona Cardinals running back Kenyan Drake holds up four fingers celebrates his fourth touchdown of the game in front of sideline photographers in the second half against the Cleveland Browns at State Farm Stadium. Mark J. Rebilas-USA TODAY Sports

Though the Cardinals have been out of the playoff picture for some time now, they were able to play the spoiler to the Browns’ season last week in Arizona. The 38-24 win was the Cardinals’ largest margin of victory this season, which gives them something positive to build off of for 2020’s campaign. Meanwhile, the Seahawks got back on top of the NFC West with a road win over the Panthers. Although every game is important, Seattle’s division title hopes will come down to next week’s fight with the 49ers. And with Bobby Wagner and Jadeveon Clowney both dealing with injuries, the degree of difficulty has increased a little bit.

The running game erupted for both teams last week. The fall of David Johnson (DFS salary $4,700) and the rise of Kenyan Drake ($6,300) was very clearly put on display as Drake rushed for 137 yards and four touchdowns. On the Seahawks’ side, Chris Carson ($8,500) filled out his lead role with 133 rushing yards and two touchdowns of his own. Though, this week both defenses rank in the bottom four for passing yards allowed. Kyler Murray ($6,100) and Russell Wilson ($7,000) will both have an opportunity to shine, though the latter’s experience and skill should propel Seattle to victory.

When they met back in Week 4, the Seahawks won 27-10. I’d expect a similar outcome, even 12 weeks later. Both teams have hit the over more often than not, but, while this is projected to be the highest-scoring game of the week, there’s a good possibility that the Seahawks defense shuts down the Cardinals offense. I’ll take Seattle to cover and the under.

All odds provided by DraftKings Sportsbook and all odds subject to change.

Cardinals at Seahawks

Betting Odds

Point Spread: Cardinals +9.5
Total Points: 51
Money Line: Cardinals +320; Seahawks -385


Overall: Cardinals 4-9-1; Seahawks 11-3
ATS: Cardinals 8-6; Seahawks 7-6-1
O/U: Cardinals 8-6; Seahawks 8-6

Injury Report


Questionable: WR Christian Kirk (ankle), G Justin Pugh (back), DT Caraun Reid (knee)


Doubtful: DE Jadeveon Clowney (core), S Quandre Diggs (ankle)

Questionable: T Duane Brown (knee, biceps), CB Shaquill Griffin (hamstring), LB Mychal Kendricks (hamstring)

Betting Trends

  • The Cardinals have lost each of their last 12 games against teams that held a winning record.
  • The Cardinals have covered the spread in each of their last four games against the Seahawks at CenturyLink Field.
  • Each of the last four games between the Cardinals and Seahawks at CenturyLink Field have gone OVER the total points line.

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Odds and lines subject to change. See website for details.