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DeAndre Hopkins doesn’t practice in run up to Week 4

Cardinals WR DeAndre Hopkins is dealing with an ankle injury heading into Week 4. We break down his injury status during the week.

Wide receiver DeAndre Hopkins of the Arizona Cardinals runs with the football past defensive back Chris Jones of the Detroit Lions in the NFL game at State Farm Stadium on September 27, 2020 in Glendale, Arizona. Photo by Christian Petersen/Getty Images

Friday update: Hopkins appears to have missed another practice on Friday, as he wasn’t seen during the open portion of practice, per Kyle Odergard of the team’s site. This isn’t good for Hopkins’ status against the Panthers, but teams will often take their start receivers up to game-time, as their ability often eclipses their need for practice reps. We will keep you updated.

If he can’t play, Christian Kirk, who is trending toward playing, Andy Isabella and Larry Fitzgerald are the likely receivers to see an uptick, while Kenyan Drake will again be relied on heavily as a runner.

Thursday PM update: The Cardinals released their Thursday injury report and Hopkins was officially a DNP for the day. Friday will be big for him.

The Arizona Cardinals are traveling to face the Carolina Panthers in Week 4, and they could potentially be shorthanded in a big way. Wide receiver DeAndre Hopkins did not practice on Wednesday and he went inside on Thursday as practice was getting started, per reporter Darren Urban. He appeared on the Wednesday injury report with an ankle injury.

Hopkins did not appear to come out of the Cardinals Week 3 game with an injury, so it’s not entirely clear how significant this injury is. Missing two straight days is not ideal, but if he gets back on Friday, it will be less of a concern for Sunday.

The news comes as fellow wide receiver Christian Kirk did return to practice to start the week. He was listed as limited on Wednesday after missing last week with a groin injury. If he continues in limited fashion, he’ll likely show up as questionable on Friday’s final injury report for Week 4.