Postgame update: The 49ers believe Wilson suffered a high ankle sprain, per Kyle Shanahan.
4th quarter update: The 49ers have announced Wilson is downgraded to OUT for the rest of the game.
UPDATE: The 49ers have announced Wilson is questionable to return with an ankle injury.
San Francisco 49ers running back Jeff Wilson is having a monster game, but might not be able to close it out. Wilson just scored his third rushing touchdown of the game, but a defender rolled up his left foot in the end zone. Wilson was down and in pain but eventually was able to limp off the field under is own power. He has since taken a cart from the sideline to the locker room.
Wilson had 112 yards on 17 carries at the time of the injury. JaMycal Hasty had one carry and one reception in the second quarter and would seem likely to get starting work in place of Wilson. Jerick McKinnon is also available but has not touched the ball through the first half of the game.