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What 49ers injuries could mean for the team’s fantasy prospects moving forward

We go over how the 49ers’ many injuries could affect the fantasy football world.

San Francisco 49ers running back Raheem Mostert receives the hand off from quarterback Jimmy Garoppolo during the first quarter in the NFC Championship Game against the Green Bay Packers at Levi’s Stadium. Kyle Terada-USA TODAY Sports

Monday update: Kyle Shanahan met with the media and updated various player injuries.

Jimmy Garoppolo: His high ankle sprain isn’t serious and he has a chance at playing this week
Tevin Coleman: Has a knee sprain that Shanahan is concerned about, but still awaiting MRI results
Raheem Mostert: Out this week with MCL sprain
Nick Bosa: Waiting on MRI results for potential torn ACL

The San Francisco 49ers have kicked off the 2020 NFL season with a 1-1 record, but things could start trending in the wrong direction for them because of their growing list of injured players. The 49ers are missing key players on both sides of the ball and could struggle to win games and compete in the NFC West.

Jimmy Garoppolo, Raheem Mostert, Tevin Coleman, George Kittle, Richard Sherman, and Nick Bosa are all dealing with injuries. The severity of the issues each player is dealing with aren’t all clear at this point, but any of them missing more than a couple games early in the season have major fantasy football implications. We’ll go over what you should look out for in fantasy football here.

Injury timelines

Garoppolo: Has a high ankle sprain that could cost him as much as 4-6 weeks.
Mostert: Potentially a sprained MCL that could cost him multiple games.
Coleman: Extent of knee injury isn’t clear, but believed to be less serious.
Kittle: Missed Week 2 with an MCL sprain, and status is not clear for Week 3.
Sherman: Placed on short term IR with calf strain, so out through at least Week 4.
Bosa: Believed to have torn his ACL, which would end his season.

Nick Mullens gets to play on the big stage

Garoppolo is dealing with a high ankle sprain and could miss 4-6 weeks, and that means there will be a change under center. While C.J. Beathard and Mullens have filled in for Garoppolo in the past, Mullens is second on the depth chart and will likely start against the New York Giants in Week 3. Mullens ranked third in yards per completion (12.9) in 2018 and isn’t shy about taking shots down the field. He could be worth a waiver wire pickup in deeper leagues if another quarterback you have is dealing with an injury, even if he doesn’t start for long.

More touches for Jerick McKinnon

McKinnon was somewhat of an enigma at the beginning of season, but that could change soon. The running back has missed two years of football while dealing with injuries but could be on the brink of becoming a feature back for the first time in a long time. It appears like Mostert might have sprained his MCL against the New York Jets in Week 2, and Coleman is dealing with a less serious knee injury. McKinnon is averaging 16.8 yards per cary in 2020. It’s safe to say that he’ll be more of a focal point than Jeff Wilson Jr., who has 93 career rushing yards.

The return of Jordan Reed’s glory days

The Washington Football Team finally cut the oft-injured Reed in February, but he’s thriving in San Francisco while Kittle is out with a knee injury. Reed caught two touchdowns in Week 2 and could become a key pass catcher for the 49ers if Kittle’s absence is extended. San Francisco’s lack of depth at wide receiver could benefit Reed moving forward.

No more elite defense

Bosa’s injury might be an ACL tear, and he entered 2020 as one of the frontrunners to win Defensive Player of the Year. He’s the heart and soul of San Francisco’s fearsome offensive line and helps put a ton of pressure on opposing quarterbacks and running backs. Then there’s Sherman. While his calf injury is less severe than Bosa’s ailment, not having one of the highest-graded cornerbacks in the NFL available to match up against the opposition’s top wide receiver will be difficult. I’m not saying the 49ers will be bad, but don’t expect them to be nearly as reliable in season-long fantasy or DFS.