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Opening odds for Colts vs. Bills in the Wild Card Round of the 2021 NFL Playoffs

We’ve got an early look at the point spread, total, and moneyline odds for this AFC Wild Card Round playoff matchup between the Indianapolis Colts and Buffalo Bills.

Buffalo Bills quarterback Josh Allen (17) throws a pass against the Miami Dolphins in the first quarter at Bills Stadium. Mark Konezny-USA TODAY Sports

After 17 weeks of regular season football, the AFC East champion, Buffalo Bills will take on the Indianapolis Colts in the Wild Card round of the 2021 NFL Playoffs. The Bills are making their second-straight playoff appearance, but will be the second seed. Meanwhile, the Colts will be the newly-added seventh seed, which was added this past offseason.

Here’s a look at the opening odds of this matchup between the Indianapolis Colts and Buffalo Bills in the first round of the 2020 NFL Playoffs. Odds courtesy of DraftKings Sportsbook.

Indianapolis Colts @ Buffalo Bills

Point spread: Bills -6.5
Point total: 51.5
Moneyline: Colts +235, Bills -305

The Bills started off the 2020 NFL regular season with a record of 4-0, which set the tone for the rest of the season. Buffalo saw third-year quarterback Josh Allen take a major in his development and be in the conversation for the league’s MVP. Allen completed 69.2 percent of his passes 4,544 yards, 37 touchdowns, and 10 interceptions. He was also a factor in the running game with 418 yards and eight scores on the ground.

A majority of Allen’s touchdown passes went to star wide receiver Stefon Diggs, who had 127 receptions for 1,535 yards and eight touchdowns in his first season with the Bills.

As for the Colts (11-5), they defeated the Jacksonville Jaguars 28-14 in Week 17 to clinch the final wildcard spot in the AFC. This season, Indianapolis head coach Frank Reich turned around the career of veteran quarterback Philip Rivers. Rivers completed 68.2 percent of his passes for 4,005 yards, 23 touchdowns and 10 interceptions.

The Colts also got a tremendous regular season from rookie running back Jonathan Taylor. Taylor had a rough first half but turned it on for the last eight games of the season. He had a career-high 253 yards on 30 carries and two touchdowns against the Jags. Additionally, the Colts have a solid defense led by DeForest Bucker and Darius Leonard, who will have their hands full with Josh Allen next weekend.

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