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Report: Saquon Barkley week-to-week with low-ankle sprain heading into Week 6

Giants running back Saquon Barkley suffered an low-ankle injury in Week 5 of the 2021 NFL season. Here are the latest updates.

New York Giants v New Orleans Saints
Saquon Barkley of the New York Giants warms up before a game against the New Orleans Saints at the Caesars Superdome on October 03, 2021 in New Orleans, Louisiana.
Photo by Jonathan Bachman/Getty Images

Post-game update: Barkley appears to have avoided a high-ankle sprain, and instead has a low-ankle sprain that has him week-to-week, per NFL Network’s Ian Rapoport. It doesn’t look good for him in Week 6 at home against the Rams, but he could possibly return against the Panthers in Week 6 if all goes well.

The New York Giants might be without star running back Saquon Barkley for the rest of a pivotal Week 5 contest against the Dallas Cowboys. The running back limped off the field after suffering an ankle injury in the first quarter.

Barkley was dealing with some nagging leg pain during his comeback from an ACL injury, but he did suit up in every game this season. If he cannot play, the Giants are losing a huge weapon offensively. He had two carries for nine yards and one target before exiting the game.

The Giants eventually carted Barkley to the locker room and have ruled him out for the game. It’s yet another unfortunate setback in Barkley’s young career. He’s struggled this season, managing just 3.6 yards per carry in the first four games of the season. The Giants entered the game against the Cowboys 1-4 and will now have to try to find a win without their best offensive player.