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(Updated) Flex rankings for Week 6 fantasy football

We take you through some of the best fantasy football flex plays going in Week 6.

Austin Ekeler #30 of the Los Angeles Chargers carries the ball during a 47-42 win over the Cleveland Browns at SoFi Stadium on October 10, 2021 in Inglewood, California. Photo by Harry How/Getty Images

Sunday update: Inactives have been removed and I’ve made some adjustments for the windy game in Cleveland. Good luck!

Week 6 kicks off tonight, as the Philadelphia Eagles host the Tampa Bay Buccaneers. Will Tom Brady continue his ascent on the record books? He currently is on pace for 5,006 passing yards, 51 touchdown passes and 6 interceptions. Jalen Hurts isn’t on that kind of pace, but he has yet to fall below QB12 in any week where he played a whole game in his career.

Both have fantasy appeal as usual tonight, as do a few other plays. Check out my flex rankings based on .5 PPR scoring.

Notable injuries

Tua Tagovailoa, Dolphins

Tagovailoa was activated and has a chance to play this week in London. We’ll need to keep an eye on his practice status.

Tom Brady, Buccaneers

Brady is dealing with a thumb injury, but should be able to play through it. He suffered the injury in a game in which he threw five touchdowns, so he should be okay.

Russell Wilson, Seahawks

Wilson will be out for a while due to his finger injury. Geno Smith will take over in his place.

Daniel Jones, Giants

Jones is in the concussion protocol. If he can’t get cleared in time, Mike Glennon will face the Rams.

Christian McCaffrey, Panthers

McCaffrey was able to practice last week and appeared close to playing. He should be even closer this week and would get a good matchups with the Vikings.

Dalvin Cook, Vikings

Cook was questionable last week and didn’t play. It would appear that he has a chance to play this week, but we’ll need to watch the practice reports.

Saquon Barkley, Giants

Barkley appears to have avoided a high-ankle sprain, but his chances of playing this week are about nil. Devonte Booker will lead the way while he is out.

Clyde Edwards-Helaire, Chiefs

Edwards-Helaire will miss at least three weeks on injured reserve. Darrel Williams will take the lead role until he returns.

Damien Harris, Patriots

Harris is considered day-to-day with a chest injury and has a shot to play this week.

Giants wide receivers

Sterling Sheperd, Darius Slayton, Kenny Golladay and Kadarius Toney all have some degree of injury at the moment. Maybe all four suit up this week, but we are very much in wait to see mode.

JuJu Smith-Schuster, Steelers

Smith-Schuster is done for the season with a shoulder injury. Chase Claypool and Diontae Johnson will lead the way.

Quintez Cephus, Lions

Cephus has a broken collarbone and was put on I.R. Rookie Amon-Ra St. Brown will get the WR1 job, but Tyrell Williams could return as early as this week.

Sammy Watkins, Ravens

Watkins suffered a hamstring injury in Week 5. His status is unclear at this time, but Devin Duvernay would likely see a slight bump with him out.

Julio Jones, Titans

Jones is dealing with a hamstring injury and his coach wouldn’t commit to him practicing this week. A.J. Brown should see more work than he did last week after coming off the same injury.

Rob Gronkowski, Buccaneers

Head coach Bruce Arians said there was a slight chance Gronkowski could play Thursday, but that doesn’t appear to be the case. Week 7 does sound realistic though.

Dallas Goedert, Eagles

Goedert has been placed on the COVID-19 list. With a short turnaround for Thursday night, his chances to play don’t appear great. Zach Ertz gets a boost.

Week 6 flex rankings

Week 7 Fantasy Football FLEX Rankings

Rk Name Team Position Opp
Rk Name Team Position Opp
1 Derrick Henry TEN RB vs KC
2 Darrell Henderson Jr. LAR RB vs DET
3 Davante Adams GB WR vs WAS
4 Aaron Jones GB RB vs WAS
5 Alvin Kamara NO RB @ SEA
6 Jonathan Taylor IND RB @ SF
7 Tyreek Hill KC WR @ TEN
8 Cooper Kupp LAR WR vs DET
9 Leonard Fournette TB RB vs CHI
10 Travis Kelce KC TE @ TEN
11 Josh Jacobs LV RB vs PHI
12 Damien Harris NE RB vs NYJ
13 Joe Mixon CIN RB @ BAL
14 D.J. Moore CAR WR @ NYG
15 Chuba Hubbard CAR RB @ NYG
16 Calvin Ridley ATL WR @ MIA
17 DeAndre Hopkins ARI WR vs HOU
18 Deebo Samuel SF WR vs IND
19 Mike Evans TB WR vs CHI
20 Ja'Marr Chase CIN WR @ BAL
21 A.J. Brown TEN WR vs KC
22 Terry McLaurin WAS WR @ GB
23 D'Andre Swift DET RB @ LAR
24 Cordarrelle Patterson ATL RB @ MIA
25 Darrel Williams KC RB @ TEN
26 Chris Godwin TB WR vs CHI
27 D.K. Metcalf SEA WR vs NO
28 Marquise Brown BAL WR vs CIN
29 James Conner ARI RB vs HOU
30 Brandin Cooks HOU WR @ ARI
31 Miles Sanders PHI RB @ LV
32 Mark Andrews BAL TE vs CIN
33 Elijah Mitchell SF RB vs IND
34 Courtland Sutton DEN WR @ CLE
35 Jaylen Waddle MIA WR vs ATL
36 Robert Woods LAR WR vs DET
37 Antonio Gibson WAS RB @ GB
38 Devontae Booker NYG RB vs CAR
39 Mike Davis ATL RB @ MIA
40 Darren Waller LV TE vs PHI
41 DeVonta Smith PHI WR @ LV
42 D'Ernest Johnson CLE RB vs DEN
43 Kyle Pitts ATL TE @ MIA
44 Tee Higgins CIN WR @ BAL
45 Michael Pittman Jr. IND WR @ SF
46 Tyler Lockett SEA WR vs NO
47 Jakobi Meyers NE WR vs NYJ
48 Chase Edmonds ARI RB vs HOU
49 Henry Ruggs III LV WR vs PHI
50 Darnell Mooney CHI WR @ TB
51 Javonte Williams DEN RB @ CLE
52 Alex Collins SEA RB vs NO
53 Dallas Goedert PHI TE @ LV
54 Mike Gesicki MIA TE vs ATL
55 Allen Robinson II CHI WR @ TB
56 Melvin Gordon III DEN RB @ CLE
57 Michael Carter NYJ RB @ NE
58 Noah Fant DEN TE @ CLE
59 Mecole Hardman KC WR @ TEN
60 T.J. Hockenson DET TE @ LAR
61 Corey Davis NYJ WR @ NE
62 Christian Kirk ARI WR vs HOU
63 AJ Dillon GB RB vs WAS
64 Myles Gaskin MIA RB vs ATL
65 Tim Patrick DEN WR @ CLE
66 Tyler Higbee LAR TE vs DET
67 Marquez Callaway NO WR @ SEA
68 J.D. McKissic WAS RB @ GB
69 Devonta Freeman BAL RB vs CIN
70 Rondale Moore ARI WR vs HOU
71 Odell Beckham Jr. CLE WR vs DEN
72 Robby Anderson CAR WR @ NYG
73 A.J. Green ARI WR vs HOU
74 Hunter Renfrow LV WR vs PHI
75 Rashod Bateman BAL WR vs CIN
76 Khalil Herbert CHI RB @ TB
77 Hunter Henry NE TE vs NYJ
78 Tyler Boyd CIN WR @ BAL
79 Darius Slayton NYG WR vs CAR
80 Rhamondre Stevenson NE RB vs NYJ
81 Mark Ingram II HOU RB @ ARI
82 Brandon Aiyuk SF WR vs IND
83 Ricky Seals-Jones WAS TE @ GB
84 Nelson Agholor NE WR vs NYJ
85 Amon-Ra St. Brown DET WR @ LAR
86 Jamison Crowder NYJ WR @ NE
87 Jamaal Williams DET RB @ LAR
88 Zach Ertz ARI TE vs HOU
89 Quez Watkins PHI WR @ LV
90 Bryan Edwards LV WR vs PHI
91 Van Jefferson LAR WR vs DET
92 Zach Pascal IND WR @ SF
93 Allen Lazard GB WR vs WAS
94 Sony Michel LAR RB vs DET
95 Kalif Raymond DET WR @ LAR
96 DeVante Parker MIA WR vs ATL
97 Damien Williams CHI RB @ TB
98 O.J. Howard TB TE vs CHI
99 David Johnson HOU RB @ ARI
100 Kenneth Gainwell PHI RB @ LV
101 Jarvis Landry CLE WR vs DEN
102 Jalen Reagor PHI WR @ LV
103 Donovan Peoples-Jones CLE WR vs DEN
104 Kendrick Bourne NE WR vs NYJ
105 Le'Veon Bell BAL RB vs CIN
106 Kenyan Drake LV RB vs PHI
107 Dante Pettis NYG WR vs CAR
108 DeSean Jackson LAR WR vs DET
109 Chris Moore HOU WR @ ARI
110 Randall Cobb GB WR vs WAS
111 Salvon Ahmed MIA RB vs ATL
112 Robert Tonyan GB TE vs WAS
113 Tyler Johnson TB WR vs CHI
114 Nyheim Hines IND RB @ SF
115 Ronald Jones II TB RB vs CHI
116 Nico Collins HOU WR @ ARI
117 Kendall Hinton DEN WR @ CLE
118 Mo Alie-Cox IND TE @ SF
119 Evan Engram NYG TE vs CAR
120 Cole Kmet CHI TE @ TB
121 Russell Gage ATL WR @ MIA
122 Ty'Son Williams BAL RB vs CIN
123 Ty Johnson NYJ RB @ NE
124 C.J. Uzomah CIN TE @ BAL
125 Demetric Felton CLE RB vs DEN
126 Trey Sermon SF RB vs IND
127 Elijah Moore NYJ WR @ NE
128 Ross Dwelley SF TE vs IND
129 Demarcus Robinson KC WR @ TEN
130 Malcolm Brown MIA RB vs ATL
131 Gerald Everett SEA TE vs NO
132 DeeJay Dallas SEA RB vs NO
133 David Njoku CLE TE vs DEN
134 Jonnu Smith NE TE vs NYJ
135 Dyami Brown WAS WR @ GB
136 Austin Hooper CLE TE vs DEN
137 Kenny Stills NO WR @ SEA
138 Anthony Firkser TEN TE vs KC
139 Byron Pringle KC WR @ TEN
140 Freddie Swain SEA WR vs NO
141 Josh Gordon KC WR @ TEN
142 Rashaad Penny SEA RB vs NO
143 Phillip Lindsay HOU RB @ ARI
144 Jerick McKinnon KC RB @ TEN
145 Adam Humphries WAS WR @ GB
146 Cameron Brate TB TE vs CHI
147 John Ross NYG WR vs CAR
148 Royce Freeman CAR RB @ NYG
149 Hayden Hurst ATL TE @ MIA
150 Devin Duvernay BAL WR vs CIN
151 Giovani Bernard TB RB vs CHI
152 Marlon Mack IND RB @ SF
153 Jeremy McNichols TEN RB vs KC
154 KhaDarel Hodge DET WR @ LAR
155 Nick Westbrook-Ikhine TEN WR vs KC
156 Samaje Perine CIN RB @ BAL
157 Jack Doyle IND TE @ SF
158 Marquise Goodwin CHI WR @ TB
159 Jaret Patterson WAS RB @ GB
160 Brandon Bolden NE RB vs NYJ
161 Adam Trautman NO TE @ SEA
162 Keelan Cole Sr. NYJ WR @ NE
163 Tevin Coleman NYJ RB @ NE
164 Rashard Higgins CLE WR vs DEN
165 Albert Wilson MIA WR vs ATL
166 Chris Conley HOU WR @ ARI
167 Mohamed Sanu Sr. SF WR vs IND
168 DeAndre Carter WAS WR @ GB
169 Preston Williams MIA WR vs ATL
170 Ian Thomas CAR TE @ NYG
171 Juwan Johnson NO TE @ SEA
172 Tommy Tremble CAR TE @ NYG
173 Chris Evans CIN RB @ BAL
174 Elijhaa Penny NYG RB vs CAR
175 Collin Johnson NYG WR vs CAR
176 Kyle Juszczyk SF RB vs IND
177 Olamide Zaccheaus ATL WR @ MIA
178 Will Dissly SEA TE vs NO
179 Anthony Schwartz CLE WR vs DEN
180 Harrison Bryant CLE TE vs DEN
181 Jordan Akins HOU TE @ ARI
182 JaMycal Hasty SF RB vs IND
183 Ryan Griffin NYJ TE @ NE
184 Marcus Johnson TEN WR vs KC
185 Ty Montgomery NO RB @ SEA
186 Pharaoh Brown HOU TE @ ARI
187 Josh Reynolds TEN WR vs KC
188 Mack Hollins MIA WR vs ATL
189 Travis Homer SEA RB vs NO
190 Kyle Rudolph NYG TE vs CAR
191 N'Keal Harry NE WR vs NYJ
192 James Proche II BAL WR vs CIN
193 Tajae Sharpe ATL WR @ MIA
194 Tre'Quan Smith NO WR @ SEA
195 Wayne Gallman Jr. ATL RB @ MIA
196 Foster Moreau LV TE vs PHI
197 Auden Tate CIN WR @ BAL
198 Ashton Dulin IND WR @ SF
199 Kylin Hill GB RB vs WAS
200 Damiere Byrd CHI WR @ TB
201 Marcedes Lewis GB TE vs WAS
202 Jalen Richard LV RB vs PHI
203 Zay Jones LV WR vs PHI
204 Durham Smythe MIA TE vs ATL
205 Danny Amendola HOU WR @ ARI
206 MyCole Pruitt TEN TE vs KC
207 Geoff Swaim TEN TE vs KC
208 Equanimeous St. Brown GB WR vs WAS
209 Greg Ward PHI WR @ LV
210 Peyton Barber LV RB vs PHI
211 Gary Brightwell NYG RB vs CAR
212 Josh Oliver BAL TE vs CIN
213 Braxton Berrios NYJ WR @ NE
214 Shi Smith CAR WR @ NYG
215 Lee Smith ATL TE @ MIA
216 Denzel Mims NYJ WR @ NE
217 Dax Milne WAS WR @ GB
218 Alec Ingold LV RB vs PHI
219 Penny Hart SEA WR vs NO
220 Artavis Pierce CHI RB @ TB
221 Geronimo Allison DET WR @ LAR
222 Jonathan Ward ARI RB vs HOU
223 Travis Benjamin SF WR vs IND
224 Devine Ozigbo NO RB @ SEA
225 Willie Snead IV LV WR vs PHI
226 Boston Scott PHI RB @ LV
227 Alex Erickson CAR WR @ NYG
228 Trent Sherfield SF WR vs IND
229 Trinity Benson DET WR @ LAR
230 Amari Rodgers GB WR vs WAS
231 Phillip Dorsett II SEA WR vs NO
232 Patrick Ricard BAL RB vs CIN
233 Eno Benjamin ARI RB vs HOU
234 Khari Blasingame TEN RB vs KC
235 Rex Burkhead HOU RB @ ARI
236 John Bates WAS TE @ GB
237 Jesse James CHI TE @ TB
238 Alex Armah Jr. NO RB @ SEA
239 Adam Shaheen MIA TE vs ATL
240 J.J. Taylor NE RB vs NYJ
241 Mike Strachan IND WR @ SF
242 Christian Blake ATL WR @ MIA
243 Ryan Nall CHI RB @ TB
244 Deon Yelder TB TE vs CHI
245 Jack Stoll PHI TE @ LV
246 J.J. Arcega-Whiteside PHI WR @ LV
247 Jaelon Darden TB WR vs CHI
248 Keith Smith ATL RB @ MIA
249 Blake Bell KC TE @ TEN
250 Jakob Johnson NE RB vs NYJ
251 Tom Kennedy DET WR @ LAR
252 Miles Boykin BAL WR vs CIN
253 Ameer Abdullah CAR RB @ NYG
254 Jakeem Grant Sr. CHI WR @ TB
255 Isaiah Ford MIA WR vs ATL
256 Mike Thomas CIN WR @ BAL
257 Cyril Grayson Jr. TB WR vs CHI
258 Keke Coutee IND WR @ SF
259 Keith Kirkwood CAR WR @ NYG
260 Trayveon Williams CIN RB @ BAL
261 Buddy Howell LAR RB vs DET
262 Lil'Jordan Humphrey NO WR @ SEA
263 Aaron Parker CAR WR @ NYG
264 Garrett Griffin NO TE @ SEA
265 Richard Rodgers PHI TE @ LV
266 Antonio Gandy-Golden WAS WR @ GB
267 Mason Kinsey TEN WR vs KC