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Week 6 is highlighted by the Red River Rivalry between the No. 6 Oklahoma Sooners and No. 21 Texas Longhorns, but that isn’t the only good matchup we have to look forward to. After both suffering losses in Week 5, No. 13 Arkansas takes on No. 17 Ole Miss with both teams looking for bounce-back wins. The biggest matchup of the weekend is No. 3 Penn State taking on No. 4 Iowa with the winner likely to remain in the Top Four and with a CFP berth in sight. No. 1 Alabama takes on Texas A&M and No. 2 Georgia takes on No. 18 Auburn.
Here are the latest opening lines for Week 6 of the 2021 college football season at opening from Circa Sports.
No. 1 Alabama vs. Texas A&M
Point spread: Alabama -16
Point total: 49.5
No. 2 Georgia vs. No. 18 Auburn
Point spread: Georgia -16
Point total: 48.5
No. 3 Penn State vs. No. 4 Iowa
Point spread: Pick ‘em
Point total: 43.5
Temple vs. No. 5 Cincinnati
Point spread: Cincinnati -28
Point total: 54.5
No. 6 Oklahoma vs. No. 21 Texas (Cotton Bowl)
Point spread: Oklahoma -3
Point total: 63.5
Maryland vs. No. 7 Ohio State
Point spread: Ohio State -21
Point total: 72.5
No. 9 Michigan vs. Nebraska
Point spread: Michigan -1
Point total: 53.5
Boise State vs. No. 10 BYU
Point spread: BYU -1
Point total: 57.5
No. 11 Michigan State vs. Rutgers
Point spread: MSU -6
Point total: 47.5
No. 13 Arkansas vs. No. 17 Ole Miss
Point spread: Ole Miss -2
Point total: 71.5
No. 14 Notre Dame vs. Virginia Tech
Point spread: Pick ‘em
Point total: 44.5
No. 15 Coastal Carolina vs. Arkansas State
Point spread: Pick ‘em
Point total: 44.5
LSU vs. No. 16 Kentucky
Point spread: Kentucky -2.5
Point total: 51.5
No. 19 Wake Forest vs. Syracuse
Point spread: Wake -11
Point total: 61.5
Vanderbilt vs. No. 20 Florida
Point spread: Florida -35
Point total: 63.5
Stanford vs. No. 22 Arizona State
Point spread: ASU -12
Point total: 51.5
No. 24 SMU vs. Navy
Point spread: SMU -15
Point total: 57.5
New Mexico vs. No. 25 San Diego State
Point spread: SDSU -18
Point total: 43.5
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