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Panthers vs. Bills game picks, best bets for Week 15 NFL season

We take a look at the best bets available for Panthers-Bills Week 15 matchup available on DraftKings Sportsbook, including our favorite player prop.

Buffalo Bills v Tampa Bay Buccaneers Photo by Julio Aguilar/Getty Images

The Carolina Panthers couldn’t be visiting at a better time for the Buffalo Bills. A popular preseason pick to go all the way to the Super Bowl, the Bills have slipped lately, losing their last three of their last four games to fall to 7-6 on the season. It’s to the point now where another loss could cost them a trip to the postseason. But they should bounce back this week. The Bills are already big favorites over the struggling Panthers, favored by double digits in this one. Kickoff is at 1:00 p.m. ET on Sunday.

Here, we’ll take a look at our picks for best bets for the Panthers-Bills in Week 15 of the NFL season. Odds come via DraftKings Sportsbook.

Panthers vs. Bills Week 15 odds

Spread: Bills -10.5
Point total: 44.5
Moneyline: Panthers +375, Bills -510

Our picks for Panthers vs. Bills

Pick against the spread: Bills -10.5

The Panthers have looked awful in their last three games, even losing to the Falcons last week. They have covered the spread in eight of their last nine road games as underdogs, but that feels like a huge stretch this week.

Over/under: Under 44.5

Six of the Bills’ last seven games against NFC teams have gone over, but for that to happen here, the Panthers offense would have to score points of their own. Even Buffalo’s offense has just been so-so lately, making it hard to get to 45 points in this one.

Preferred player prop: Gabriel Davis anytime TD (+210)

We’re going to roll with the hot hand of Gabriel Davis, who has scored a touchdown in back-to-back games for the Buffalo Bills. Last week against the Tampa Bay Buccaneers, the young wide receiver had five receptions (eight targets) for 43 yards and a score. He could find his way into the end zone on Sunday as the Panthers’ defense will be focused on Stefon Diggs, Dawson Knox, and even Emmanuel Sanders to a certain extent. At +210, this seems like a nice longshot bet to take a shot on for a couple of dollars.

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