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Full list of opening odds for the Sweet 16 round of the 2021 NCAA Tournament

Here’s the complete list of odds for the Sweet 16 round of the 2021 NCAA Tournament coming to you from Indianapolis.

Syracuse Orange reacts to drafting the West Virginia Mountaineers in the second round of the 2021 NCAA Tournament at Bankers Life Fieldhouse. Trevor Ruszkowski-USA TODAY Sports

The NCAA Tournament is advancing through the first weekend and Sweet 16 matchups are being finalized. We’ve had some big upsets along the way, and we already have our first double digit seed into the second weekend of the tournament. No. 11 Syracuse held off No. 3 West Virginia 75-72 and will face No. 2 Houston in the Sweet 16. We’re guaranteed at least one more double digit when No. 11 UCLA faces No. 14 Abilene Christian on Monday.

Odds are starting to arrive for third round contests. The second round does not wrap until late Monday night, but we already have lines for the confirmed third round matchups. The Sweet 16 tips at 2 p.m. next Saturday. In the meantime, here is where odds are opening for all the third round games in the 2021 NCAA Tournament from DraftKings Sportsbook.

South region

No. 5 Villanova vs. No. 1 Baylor
Point spread: Baylor -6.5
Total: 137.5
Moneyline: Baylor -295, Villanova +240

No. 15 Oral Roberts vs. No. 3 Arkansas
Point spread: Arkansas -11
Total: 159.5
Moneyline: Arkansas -670, Oral Roberts +475

Midwest region

No. 11 Syracuse vs. No. 2 Houston
Point spread: Houston -7
Total: 139.5
Moneyline: Houston -315, Syracuse +255

No. 12 Oregon State vs. No. 8 Loyola Chicago
Point spread: Loyola -7
Total: 127
Moneyline: Loyola -315, Oregon State +255

West region

No. 5 Creighton vs. No. 1 Gonzaga
Point Spread: Gonzaga -13.5
Total: 158.5
Moneyline: Gonzaga -1115, Creighton +700

No. 7 Oregon vs. No. 6 USC
Point Spread: USC -1.5
Total: 138
Moneyline: USC -124, Oregon +104

East region

No. 11 UCLA vs. No. 2 Alabama
Point Spread: Alabama -6
Total: 144
Moneyline: Alabama -265, UCLA +215

No. 4 Florida State vs. No. 1 Michigan
Point spread: Michigan -3
Total: 146.5
Moneyline: Michigan -159, Florida State +135

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