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Full Sweet 16 round picks, previews of the 2021 NCAA Tournament

We have game previews with picks for each matchup in the third round of March Madness.

A detailed view of the March Madness logo at center court as Gonzaga Bulldogs and Norfolk State Spartans players run by during the second half in the first round of the 2021 NCAA Tournament at Bankers Life Fieldhouse.  Kirby Lee-USA TODAY Sports

The NCAA Tournament is chugging along and we’re a full week into March Madness. The first round saw a record number of upsets, but plenty of college basketball’s elite are headed to the Sweet 16.

Gonzaga, Baylor, and Michigan all made it through as No. 1 seeds, and they’re joined by No. 2 seeds Houston and Alabama. No. 15 Oral Roberts is the most notable Cinderella this weekend, but No. 12 Oregon State and No. 11s UCLA and Syracuse all will look to keep the magic alive.

The Sweet 16 tips off on Saturday and by Sunday evening, we’ll have our quarterfinals set. The Elite Eight will take place Monday and Tuesday evening. Below, we’ve got all the information you need for each game of the Sweet 16 round of the 2021 NCAA Tournament. For the most current odds, you can visit DraftKings 2021 March Madness betting.

Sweet 16

Midwest

No. 12 Oregon State vs. No. 8 Loyola Chicago

Date: Saturday, Marcy 27
Time: 2:40 p.m.
Channel: CBS
Opening Odds: Loyola Chicago -7, 127
Game preview, picks

No. 11 Syracuse vs. No. 2 Houston

Date: Saturday, Marcy 27
Time: 9:55 p.m.
Channel: CBS
Opening Odds: Houston -7, 139.5
Game preview, picks

South

No. 5 Villanova vs. No. 1 Baylor

Date: Saturday, Marcy 27
Time: 5:15 p.m.
Channel: TBS
Opening Odds: Baylor -6.5, 137.5
Game preview, picks

No. 15 Oral Roberts vs. No. 3 Arkansas

Date: Saturday, Marcy 27
Time: 7:25 p.m.
Channel: TBS
Odds: Arkansas -11, 159.5
Game preview, picks

East

No. 4 Florida State vs. No. 1 Michigan

Date: Sunday, March 28
Time: 5 p.m.
Channel: CBS
Odds: Michigan -2.5, 144
Game preview, picks

No. 11 UCLA vs. No. 2 Alabama

Date: Sunday, March 28
Time: 7:15 p.m.
Channel: TBS
Odds: Alabama -6.5, 145.5
Game preview, picks

West

No. 5 Creighton vs. No. 1 Gonzaga

Date: Sunday, March 28
Time: 2:10 p.m.
Channel: CBS
Odds: Gonzaga -13.5, 158
Game preview, picks

No. 7 Oregon vs. No. 6 USC

Date: Sunday, March 28
Time: 9:45 p.m.
Channel: TBS
Odds: USC -2, 138.5
Game preview, picks