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The first weekend of college football is right around the corner, and we already have betting spreads for most of the games available for Week 1 of the 2021 college football season.
Labor Day Weekend has some quality matchups, including the Georgia Bulldogs and Clemson Tigers doing battle in Charlotte, North Carolina. DJ Uiagalelei steps in for Trevor Lawrence as the starting quarterback for the huge favorites to win a seventh-straight ACC Championship.
Also the calendar will begin with the Alabama Crimson Tide in their second home of Mercedes-Benz Stadium in Atlanta against the Miami Hurricanes. It’s technically a home game for Canes quarterback D’Eriq King, who must be working on a second doctorate degree by now, as well as head coach Manny Diaz. But you can expect most of the fans will be rooting for the Tide to roll as three-score favorites.
Here are the current odds for Week 1 of the college football season, as well as the biggest games of the 2021 season from DraftKings Sportsbook:
CFB Odds Week 1, Games of the Year
| Team | Spread | Moneyline |
|---|---|---|
| Team | Spread | Moneyline |
| Nebraska | -9.5 -124 | -385 |
| Illinois | +9.5 +102 | +280 |
| North Carolina | -6.5 -112 | -230 |
| Virginia Tech | +6.5 -109 | +180 |
| Penn State | +3.5 -110 | +123 |
| Wisconsin | -3.5 -110 | -155 |
| Western Michigan | +17.5 -110 | +550 |
| Michigan | -17.5 -110 | -1000 |
| LSU | -4.5 -108 | -195 |
| UCLA | +4.5 -113 | +150 |
| Michigan State | +6.5 -106 | +185 |
| Northwestern | -6.5 -115 | -245 |
| UTSA | +6.5 +100 | +190 |
| Illinois | -6.5 -121 | -265 |
| Indiana | +5.5 -106 | +170 |
| Iowa | -5.5 -115 | -220 |
| Oregon State | +5.5 -112 | +170 |
| Purdue | -5.5 -109 | -220 |
| Georgia | +4 -110 | +145 |
| Clemson | -4 -110 | -182 |
| Alabama | -17.5 -110 | -1000 |
| Miami Florida | +17.5 -110 | +575 |
| Notre Dame | -9.5 -124 | -400 |
| Florida State | +9.5 +102 | +285 |
| Ole Miss | -7.5 -103 | -245 |
| Louisville | +7.5 -118 | +195 |
| Purdue | -27.5 -114 | -10000 |
| UConn | +27.5 -107 | +1700 |
| Youngstown St Penguins | +19.5 -108 | +750 |
| Michigan State | -19.5 -113 | -1430 |
| Idaho | +32.5 -109 | NL |
| Indiana | -32.5 -112 | NL |
| Utah | -7.5 -107 | -265 |
| BYU | +7.5 -114 | +205 |
| Oregon | +9.5 +102 | +265 |
| Ohio State | -9.5 -125 | -375 |
| Ball State | +20.5 -110 | +850 |
| Penn State | -20.5 -110 | -2500 |
| Indiana State | +26.5 -109 | +1300 |
| Northwestern | -26.5 -112 | -5000 |
| Washington | +1.5 -113 | -105 |
| Michigan | -1.5 -107 | -117 |
| Texas | -4.5 -108 | -182 |
| Arkansas | +4.5 -113 | +140 |
| Toledo | +20.5 -105 | +800 |
| Notre Dame | -20.5 -117 | -2000 |
| Stanford | +14.5 -109 | +425 |
| USC | -14.5 -112 | -670 |
| Iowa | +4.5 -115 | +145 |
| Iowa State | -4.5 -106 | -190 |
| Illinois | +10.5 -109 | +290 |
| Virginia | -10.5 -112 | -420 |
| Cincinnati | -1.5 -103 | -110 |
| Indiana | +1.5 -120 | -110 |
| Michigan State | +17.5 -110 | +550 |
| Miami Florida | -17.5 -110 | -910 |
| Maryland | -6.5 -124 | -230 |
| Illinois | +6.5 +100 | +185 |
| Auburn | +7.5 -113 | +200 |
| Penn State | -7.5 -108 | -250 |
| Alabama | -14.5 -110 | -715 |
| Florida | +14.5 -110 | +420 |
| Purdue | +11.5 -110 | +310 |
| Notre Dame | -11.5 -110 | -480 |
| Northern Illinois | +27.5 -110 | +1700 |
| Michigan | -27.5 -110 | -10000 |
| Nebraska | +18 -112 | +575 |
| Oklahoma | -18 -109 | -1000 |
| Northwestern | -9.5 -113 | -345 |
| Duke | +9.5 -108 | +250 |
| Ohio | +15.5 -112 | +450 |
| Northwestern | -15.5 -109 | -715 |
| Indiana | -21.5 -110 | -1667 |
| Western Kentucky | +21.5 -110 | +850 |
| UCLA | -7.5 -110 | -265 |
| Stanford | +7.5 -110 | +205 |
| Villanova | +29 -109 | NL |
| Penn State | -29 -112 | NL |
| Tennessee | +16 -108 | +480 |
| Florida | -16 -113 | -770 |
| Nebraska | -5.5 -115 | -200 |
| Michigan State | +5.5 -106 | +165 |
| Wisconsin | -1.5 -103 | -110 |
| Notre Dame | +1.5 -120 | -110 |
| Illinois | +10.5 -117 | +255 |
| Purdue | -10.5 -105 | -335 |
| Indiana | +6.5 -110 | +175 |
| Penn State | -6.5 -110 | -230 |
| Minnesota | -3.5 +100 | -137 |
| Purdue | +3.5 -124 | +110 |
| Auburn | +6.5 -104 | +185 |
| LSU | -6.5 -118 | -230 |
| Northwestern | +6.5 -108 | +180 |
| Nebraska | -6.5 -113 | -235 |
| Cincinnati | +3.5 -113 | +123 |
| Notre Dame | -3.5 -108 | -150 |
| Charlotte | +15 -110 | +410 |
| Illinois | -15 -110 | -590 |
| Western Kentucky | +15.5 -108 | +450 |
| Michigan State | -15.5 -113 | -670 |
| Texas | -2.5 -110 | -129 |
| TCU | +2.5 -110 | +106 |
| Michigan | +9.5 -110 | +235 |
| Wisconsin | -9.5 -110 | -305 |
| Notre Dame | -5.5 -110 | -195 |
| Virginia Tech | +5.5 -110 | +155 |
| Oklahoma | -9.5 -125 | -400 |
| Texas | +9.5 -104 | +275 |
| Wisconsin | -17.5 -110 | -835 |
| Illinois | +17.5 -110 | +550 |
| Penn State | +3.5 -113 | +123 |
| Iowa | -3.5 -108 | -150 |
| Michigan | -2.5 -108 | -130 |
| Nebraska | +2.5 -113 | +108 |
| Georgia | -9 -110 | -335 |
| Auburn | +9 -110 | +245 |
| Alabama | -11.5 -107 | -500 |
| Texas A&M | +11.5 -114 | +325 |
| UCF | +10.5 -110 | +290 |
| Cincinnati | -10.5 -110 | -420 |
| Purdue | +14.5 -110 | +410 |
| Iowa | -14.5 -110 | -590 |
| Miami Florida | +2.5 -103 | +115 |
| North Carolina | -2.5 -120 | -139 |
| Florida | +1.5 -110 | +100 |
| LSU | -1.5 -110 | -121 |
| Michigan State | +16.5 -109 | +480 |
| Indiana | -16.5 -112 | -715 |
| Clemson | -18.5 -108 | -1115 |
| Pittsburgh | +18.5 -113 | +650 |
| Wisconsin | -10.5 -108 | -345 |
| Purdue | +10.5 -113 | +270 |
| Illinois | +20.5 +100 | +750 |
| Penn State | -20.5 -125 | -1430 |
| Northwestern | +9.5 -108 | +250 |
| Michigan | -9.5 -113 | -335 |
| USC | +3.5 -113 | +125 |
| Notre Dame | -3.5 -108 | -159 |
| Ohio State | -11 -108 | -420 |
| Indiana | +11 -113 | +300 |
| Memphis | +7.5 -125 | +195 |
| UCF | -7.5 +102 | -250 |
| Minnesota | -3.5 -105 | -152 |
| Northwestern | +3.5 -117 | +118 |
| Penn State | +10.5 -110 | +280 |
| Ohio State | -10.5 -110 | -400 |
| North Carolina | +2.5 -103 | +115 |
| Notre Dame | -2.5 -120 | -139 |
| Michigan | -6.5 -120 | -235 |
| Michigan State | +6.5 -103 | +188 |
| Purdue | +6.5 -104 | +185 |
| Nebraska | -6.5 -118 | -230 |
| Indiana | -6.5 -120 | -235 |
| Maryland | +6.5 -103 | +188 |
| Georgia | -6.5 -125 | -250 |
| Florida | +6.5 +104 | +190 |
| Indiana | +3.5 -113 | +123 |
| Michigan | -3.5 -108 | -150 |
| Iowa | -10.5 -107 | -345 |
| Northwestern | +10.5 -114 | +270 |
| Michigan State | +7.5 -124 | +185 |
| Purdue | -7.5 +100 | -240 |
| Oregon | -1.5 -106 | -114 |
| Washington | +1.5 -115 | -107 |
| Navy | +24.5 -110 | +1200 |
| Notre Dame | -24.5 -110 | -3335 |
| LSU | +21.5 -110 | +900 |
| Alabama | -21.5 -110 | -2500 |
| Auburn | +9.5 -106 | +250 |
| Texas A&M | -9.5 -114 | -335 |
| Purdue | +21.5 -110 | +900 |
| Ohio State | -21.5 -110 | -2500 |
| Illinois | +14.5 -110 | +410 |
| Minnesota | -14.5 -110 | -590 |
| Penn State | -9.5 -117 | -335 |
| Maryland | +9.5 -104 | +260 |
| North Carolina | -6.5 -120 | -235 |
| Pittsburgh | +6.5 -103 | +188 |
| Michigan | +7.5 -110 | +210 |
| Penn State | -7.5 -110 | -265 |
| Northwestern | +16.5 -109 | +480 |
| Wisconsin | -16.5 -112 | -715 |
| Maryland | -1.5 -106 | -114 |
| Michigan State | +1.5 -115 | -107 |
| Notre Dame | -7.5 -110 | -286 |
| Virginia | +7.5 -110 | +215 |
| Purdue | +1.5 -117 | -108 |
| Northwestern | -1.5 -105 | -113 |
| Georgia Tech | +14.5 -114 | +400 |
| Notre Dame | -14.5 -107 | -560 |
| Texas | -2.5 -117 | -137 |
| West Virginia | +2.5 -104 | +112 |
| Iowa State | +8.5 -114 | +225 |
| Oklahoma | -8.5 -107 | -305 |
| Minnesota | +6.5 -104 | +185 |
| Indiana | -6.5 -118 | -230 |
| Michigan State | +27 -108 | +1600 |
| Ohio State | -27 -113 | -10000 |
| Michigan | -6.5 -113 | -230 |
| Maryland | +6.5 -108 | +175 |
| Illinois | +21.5 -110 | +850 |
| Iowa | -21.5 -110 | -1667 |
| Iowa | -6.5 -120 | -250 |
| Nebraska | +6.5 -103 | +190 |
| Notre Dame | -11 -110 | -420 |
| Stanford | +11 -110 | +295 |
| Ohio State | -13 -112 | -530 |
| Michigan | +13 -109 | +350 |
| Northwestern | -6.5 -109 | -225 |
| Illinois | +6.5 -112 | +170 |
| Alabama | -16.5 -125 | -835 |
| Auburn | +16.5 -105 | +525 |
| Oklahoma | -11 -109 | -420 |
| Oklahoma State | +11 -112 | +300 |
| Penn State | -14.5 -106 | -560 |
| Michigan State | +14.5 -115 | +400 |
| Indiana | -6.5 -120 | -250 |
| Purdue | +6.5 -103 | +188 |
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