The 49ers had the worst injury luck in the league in 2020 and it was impossible to overcome as they ended up finishing last in the NFC West at 6-10. The injuries are too numerous to list them all, but Jimmy Garoppolo, Nick Bosa, George Kittle, Dee Ford, Ezekiel Ansah, Richard Sherman, and Soloman Thomas all missed big chunks of time. They’ll hope for better injury luck and a strong start to rookie QB Trey Lance’s career in 2021.
We’ll take a look at the latest DraftKings Sportsbook lines and predict if the 49ers can beat their 2021 win total. The odds below are as of June 1, 2021.
NFC West win totals
Notable offseason moves
The 49ers re-signed left tackle Trent Williams and brought in center Alex Mack. They also re-signing cornerbacks Jason Verrett, Dontae Johnson and Emmanuel Moseley and they’ll likely lose CB Richard Sherman. But the biggest move was trading up to pick QB Trey Lance third overall in the 2021 NFL Draft.
San Francisco 49ers prediction: OVER 10.5
I’m likely too high on all of the NFC West, but these are very good teams and three can easily make the playoffs while the fourth could end up getting snubbed. The 49ers, when healthy, are one of the best defenses in the league and showed they are still very good when not healthy last season. The offense without the average, but better than his backups, Jimmy Garoppolo, wasn’t great. But the team let it be known they needed to upgrade from Garoppolo after trading three first round picks to move from No. 12 to No. 3 to get Trey Lance.
Garoppolo hasn’t been able to stay healthy as it is, but it’s anybody’s guess as to when Lance will start. But the possibilities of Lance in a Kyle Shanahan offense are tremendous. We know the 49ers can win games with Garoppolo managing the offense. They can win a lot of games that way. But add in a dynamic offensive player like Lance and that offense could truly be special. Will that happen this year? Maybe, maybe not, but between the two of them, and a little injury luck, 12 wins is firmly in their grasp.
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