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NFL picks, Week 1: Predicting every game against the spread to open the 2021 NFL season

The NFL is back for the 2021 season, and that means it’s time to start picking games against the spread! Here’s my full list of Week 1 picks.

How can Pittsburgh upset Buffalo Week 1?

The first NFL Sunday is upon us! The Buccaneers opened the season with a wild 31-29 Thursday win over the Cowboys and fingers crossed that sets the tone for a fun Week 1 Sunday.

I took the points with the Cowboys to open the season 1-0. This very well could end up being my high point for picks against the spread. Finishing anywhere over .500 is an accomplishment in my books when it comes to figuring out the number each week for 16 games. But, we’re going to give it a go and pick every game against the spread each week.

All odds below come courtesy of DraftKings Sportsbook. Each week, I’ll also pull out my five best bets. These are based on Sunday morning lines, so they’re not necessarily best bets I grabbed earlier in the week before some of the current line movement.

Bills (-6.5) over Steelers
Vikings (-3) over Bengals
Titans (-2.5) over Cardinals
Bears (+8) over Rams
Raiders (+4) over Ravens

Here are all my picks for Week 1.

Cowboys vs. Bucs (-9.5): Cowboys — WIN
49ers vs. Lions (+9): 49ers
Eagles vs. Falcons (-3): Falcons
Seahawks vs. Colts (+2.5): Seahawks
Cardinals vs. Titans (-2.5): Titans
Steelers vs. Bills (-6.5): Bills
Jaguars vs. Texans (+3): Jaguars
Vikings vs. Bengals (+3): Vikings
Chargers vs. Washington (-2): Washington
Jets vs. Panthers (-3.5): Panthers
Browns vs. Chiefs (-5): Chiefs
Dolphins vs. Patriots (-3.5): Patriots
Packers vs. Saints (+3.5): Packers
Broncos vs. Giants (+3): Giants
Bears vs. Rams (-8): Bears
Ravens vs. Raiders (+4): Raiders

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