Update: Here’s the official inactives list for the Patriots Saturday. Both Harris and Hightower are playing.
Running back Damien Harris, linebacker Dont’a Hightower and wide receiver Jakobi Meyers headline a list of 11 players who are questionable for the contest. Key defensive players like Lawrence Guy, Christian Barmore and Jamie Collins are also on the list. Nick Folk is questionable as well, which could be an issue as he’s been a reliable kicker this year for New England.
Isaiah Wynn - OUT
Depending on which players ultimately do get ruled out, this could have a minimal to significant impact for the Patriots agains the Bills. Wynn being the lone inactive would just mean one less body on the offensive line, while a host of questionable players being ruled out would leave New England depleted at key spots in a playoff game.