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What is the spread for Vikings vs. Bills? Who are bettors picking? Who is the favorite?

The Bills are home favorites in Week 10 despite uncertainty surrounding Josh Allen’s availability against the Vikings.

KANSAS CITY, MO - OCTOBER 16: Stefon Diggs #14 of the Buffalo Bills looks down field against the Kansas City Chiefs at GEHA Field at Arrowhead Stadium on October 16, 2022 in Kansas City, Missouri. Photo by Cooper Neill/Getty Images

Update — The Bills are driving down the field and are ML favorites on DKSB after the Vikings kicked a FG. Perhaps the bigger storyline is the Bills spent most of the week at -3.5 and a walkoff TD would mean a 3-point win. If you were able to grab the Vikings either at +3.5 or +6.5, that was the play.

Update — Okay this line makes more sense. Vikings are -185 and the Bills are +150 as OT begins. Minnesota gets the ball first.

Update — PLOT TWIST. The Bills lost another OT coin toss. The line is moving fast but it’s now Vikings -110 and Bills -120.

Update — If you’re watching Vikings-Bills, you likely need a cigarette and not the spread/odds. The Bills almost blew the game but the Vikings are who they are. Buffalo was able to force OT with a late FG and the game is 30-30. We’ve got the ML posted on DKSB for OT at Bills -155 and Vikings +125.

The Minnesota Vikings travel to face the Buffalo Bills at Highmark Stadium in a matchup of two teams with the NFL’s best records up to this point in the season. Kickoff is set for 1:00 p.m. ET and the game will air on FOX. DraftKings Sportsbook point spread has the Bills as a 3.5-point favorite and the point total is 43.5.

After a blowout loss to the Eagles back in Week 2, the Vikings have strung together six straight wins to propel their record to 7-1. Minnesota has a firm grip on the top spot in the NFC North, and they will look to improve on their stellar 3-1 record when playing on the road. Despite the tough matchup with the Bills' defense, the Vikings could have the benefit of having health to their advantage with starter Kirk Cousins under center.

The Bills have compiled a convincing 6-2 record through this point in the season and remain one of, if not the favorite to come out of the AFC. On Sunday they will face arguably their toughest obstacle yet with the uncertainty around the game status of quarterback Josh Allen. Allen did not practice for the second-straight day this week as he nurses an elbow injury, meaning that Case Keenum could be starting under center for Sunday’s matchup.

Below is a rundown of current odds information for Vikings-Bills. You can see how the point spread, point total, and moneyline odds have all moved since the lookahead line posted last week. The three dates below are the lookahead line (Nov 2), the re-opening Sunday night (Nov 6), and the current line (Nov 10). That’s followed by betting trends and how the public is betting the matchup at DraftKings Sportsbook.

Vikings vs. Bills odds, line movement

November 13

Point spread: Bills -6.5
Point total: 46
Moneyline: Bills -275, Vikings +230

November 10

Point spread: Bills -3.5
Point total: 43.5
Moneyline: Bills -175, Vikings +150

November 6

Point spread: Bills -9.5
Point total: 49.5
Moneyline: Bills -425, Vikings +345

November 2

Point spread: Bills -9.5
Point total: 49.5
Moneyline: Bills -425, Vikings +345

Vikings vs. Bills betting trends

SU: Vikings 7-1, Bills 6-2
ATS: Vikings 3-4-1, Bills 4-3-1
O/U: Vikings 4-4, Bills 1-7

Vikings vs. Bills betting splits

Point spread: Vikings 73% handle, 61% bets
Total: Under 82% handle, Over 64% bets
Moneyline: Vikings 60% handle, Bills 56% bets