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March Madness predictions 2022: Instant picks heading into Second Round

We give our instant picks for the 2022 NCAA Men’s Basketball Tournament as second-round matchups are made official.

Memphis Tigers center Jalen Duren grabs a rebound over Boise State Broncos forward Abu Kigab during their first round NCAA Tournament matchup on Thursday, March 17, 2022 at the Moda Center in Portland, Ore. Joe Rondone/The Commercial Appeal / USA TODAY NETWORK

Ever heard “think long, think wrong?” Well, we’re firing from the hip and providing instant picks as second-round matchups are decided for the 2022 NCAA Men’s Basketball Tournament. As we know who will be playing who in the Round of 32, we’ll be picking the teams that will advance to the Sweet 16.

No deep pondering about this at all. Here are our initial, gut feeling picks for how the second round of the 2022 NCAA Men’s Basketball Tournament will shake out. This is about instinct, feel, and maybe a bit of matchup based on what we’ve seen over the first two games played by both teams in the first round.

East region

No. 1 Baylor vs. No. 8 North Carolina: North Carolina
No. 4 UCLA vs. No. 5 Saint Mary’s: Saint Mary’s
No. 7 Murray State vs. No. 15 Saint Peter’s: Murray State
No. 4 Purdue vs. No. 6 Texas: Purdue

South region

No. 1 Arizona vs. No. 9 TCU: Arizona
No. 2 Villanova vs. No. 7 Ohio State: Villanova
No. 3 Tennessee vs. No. 11 Michigan: Tennessee
No. 4 Illinois vs. No. 5 Houston: Houston

Midwest region

No. 1 Kansas vs. No. 9 Creighton: Kansas
No. 2 Auburn vs. No. 10 Miami: Auburn
No. 4 Providence vs. No. 12 Richmond: Richmond
No. 11 Iowa State vs. No. 3 Wisconsin: Iowa State

West region

No. 1 Gonzaga vs. No. 9 Memphis: Gonzaga
No. 2 Duke vs. No. 7 Michigan State: Duke
No. 3 Texas Tech vs. No. 11 Notre Dame: Texas Tech
No. 4 Arkansas vs. No. 12 New Mexico State: Arkansas