The Sweet 16 for the South region has been set with region semifinal games taking place on Thursday, March 24 from AT&T Center in San Antonio, TX.
No. 1 Arizona is the favorite to represent the South in the Final Four and made it this far by taking down Wright State and TCU. They will face No. 5 Houston in the regional semifinal on Thursday, with their odds to advance to the Final Four at +140.
The biggest surprise from the field is No. 11 Michigan, who pulled off a pair of upsets over No. 6 Colorado State and No. 3 Tennessee to get to this point. The Wolverines will be matched up against No. 2 Villanova.
Here are the odds to reach the 2022 Final Four out of the South Region from DraftKings Sportsbook:
If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL/IN/MI/NJ/PA/WV/WY), 1-800-NEXT STEP (AZ), 1-800-522-4700 (CO/NH), 888-789-7777/visit ccpg.org/chat (CT), 1-800-BETS OFF (IA), 877-8-HOPENY/text HOPENY (467369) (NY), call/text TN REDLINE 1-800-889-9789 (TN), or 1-888-532-3500 (VA). 21+ (18+ NH/WY). Physically present in AZ/CO/CT/IL/IN/IA/MI/NH/NJ/NY/PA/TN/VA/WV/WY only. Eligibility restrictions apply. See draftkings.com/sportsbook for full terms and conditions.