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Opening odds for Week 4 of the 2022 NFL season

We’ve got an early look at Week 4 point spreads as the NFL wraps up Week 3.

Jacksonville Jaguars quarterback Trevor Lawrence (16) hugs Jacksonville Jaguars running back James Robinson (25) for his touchdown score during the second quarter of a regular season game Sunday, Sept. 18, 2022 at TIAA Bank Field in Jacksonville. Corey Perrine/Florida Times-Unio / USA TODAY NETWORK

The NFL is headed into Sunday Night Football and has Monday Night Football still to play, but we’ve got some early odds to get you ready for Week 4. We’re seeing some unexpected developments across the league and the most notable might be that the Jaguars and Eagles are playing one of next week’s biggest games. Add in Chiefs-Bucs, Bills-Ravens and Rams-49ers, and it’s a heck of a week coming up.

DraftKings Sportsbook unveiled opening odds for all 18 weeks back in May after the schedule was released. Those were pulled once the regular season got underway and the sportsbook re-opened the lines for Week 4 with a lookahead line last week. Below, we’ve included the offseason opening odds, the lookahead line, and the current line once it re-opens.

Here’s our full list of Week 4 odds at DraftKings Sportsbook. We’ll update once the odds re-open Sunday evening.

Dolphins vs. Bengals

Sep 25

Point spread: Bengals -1.5
Point total: 48.5
Moneyline: Bengals -125, Dolphins +105

Sep 22

Point spread: Bengals -1.5
Point total: 48
Moneyline: Bengals -120, Dolphins +100

May 13

Opening point spread: Bengals -4.5
Opening moneyline: Bengals -195, Dolphins +165

Vikings vs. Saints

Sep 25

Point spread: Vikings -2
Point total: 44.5
Moneyline: Vikings -130, Saints +110

Sep 22

Point spread: Vikings -1
Point total: 44.5
Moneyline: Vikings -115, Saints -105

May 13

Opening point spread: Vikings -1
Opening total: 46.5
Opening moneyline: Vikings -115, Saints -105

Browns vs. Falcons

Sep 25

Point spread: Browns -3
Point total: 45.5
Moneyline: Browns -165, Falcons +140

Sep 22

Point spread: Browns -3
Point total: 45
Moneyline: Browns -170, Falcons +145

May 13

Opening point spread: N/A
Opening moneyline: N/A

Commanders vs. Cowboys

Sep 25

Point spread: Cowboys -3
Point total: 42.5
Moneyline: Cowboys -165, Commanders +140

Sep 22

Point spread: Cowboys -2.5
Point total: 43
Moneyline: Cowboys -130, Commanders +110

May 13

Opening point spread: Cowboys -5
Opening moneyline: Cowboys -235, Commanders +190

Seahawks vs. Lions

Sep 25

Point spread: Lions -6
Point total: 48
Moneyline: Lions -245, Seahawks +205

Sep 22

Point spread: Lions -5.5
Point total: 46
Moneyline: Lions -215, Seahawks +185

May 13

Opening point spread: Lions -1
Opening moneyline: Lions -120, Seahawks +100

Titans vs. Colts

Sep 25

Point spread: Colts -3
Point total: 44
Moneyline: Colts -170, Titans +145

Sep 22

Point spread: Colts -3.5
Point total:44.5
Moneyline: Colts -180, Titans +155

May 13

Opening point spread: Colts -3
Opening moneyline: Colts -155, Titans +135

Bears vs. Giants

Sep 25

Point spread: Giants -2.5
Point total: 39.5
Moneyline: Giants -140, Bears +120

Sep 22

Point spread: Giants -3
Point total: 39.5
Moneyline: Giants -165, Bears +140

May 13

Opening point spread: Giants -2.5
Opening moneyline: Giants -135, Bears +115

Jaguars vs. Eagles

Sep 25

Point spread: Eagles -7
Point total: 48
Moneyline: Eagles -305, Jaguars +255

Sep 22

Point spread: Eagles -7
Point total: 48
Moneyline: Eagles -305, Jaguars +255

May 13

Opening point spread: Eagles -6
Opening moneyline: Eagles -260, Jaguars +210

Jets vs. Steelers

Sep 25

Point spread: Steelers -3.5
Point total: 41.5
Moneyline: Steelers -170, Jets +145

Sep 22

Point spread: Steelers -3.5
Point total: 42.5
Moneyline: Steelers -175, Jets +150

May 13

Opening point spread: Steelers -3.5
Opening moneyline: Steelers -150, Jets +130

Bills vs. Ravens

Sep 25

Point spread: Bills -3
Point total: 54.5
Moneyline: Bills -170, Ravens +145

Sep 22

Point spread: Bills -4
Point total: 55
Moneyline: Bills -190, Ravens +160

May 13

Opening point spread: Bills -1
Opening moneyline: Bills -120, Ravens +100

Chargers vs. Texans

Sep 25

Point spread: Chargers -6.5
Point total: 45
Moneyline: Chargers -300, Texans +250

Sep 22

Point spread: Chargers -7
Point total: 46
Moneyline: Chargers -315, Texans +260

May 13

Opening point spread: Chargers -7.5
Opening moneyline: Chargers -350, Texans +270

Cardinals vs. Panthers

Sep 25

Point spread: Panthers -1
Point total: 45
Moneyline: Panthers -120, Cardinals +100

Sep 22

Point spread: Cardinals -3
Point total: 46.5
Moneyline: Cardinals -170, Panthers +145

May 13

Opening point spread: Cardinals -2.5
Opening moneyline: Cardinals -140, Panthers +120

Patriots vs. Packers

Sep 25

Point spread: Packers -8
Point total: 42
Moneyline: Packers -360, Patriots +295

Sep 22

Point spread: Packers -6
Point total: 42.5
Moneyline: Packers -250, Patriots +210

May 13

Opening point spread: Packers -5
Opening moneyline: Packers -235, Patriots +190

Broncos vs. Raiders

Sep 25

Point spread: Raiders -1.5
Point total: 46
Moneyline: Raiders -120, Broncos +100

Sep 22

Point spread: Raiders -1.5
Point total: 46
Moneyline: Raiders -120, Broncos +100

May 13

Opening point spread: Pick ‘em
Opening moneyline: Broncos -110, Raiders -110

Chiefs vs. Bucs

Sep 25

Point spread: Chiefs -2.5
Point total: 47.5
Moneyline: Chiefs -140, Bucs +120

Sep 22

Point spread: Chiefs -1
Point total: 48.5
Moneyline: Chiefs -115, Bucs -105

May 13

Opening point spread: Bucs -2.5
Opening moneyline: Bucs -135, Chiefs +115

Rams vs. 49ers

Sep 25

Point spread: 49ers -2
Point total: 47
Moneyline: 49ers -125, Rams +105

Sep 22

Point spread: 49ers -1
Point total: 48
Moneyline: 49ers -115, Rams -105

May 13

Opening point spread: Rams -1
Opening moneyline: Rams -120, 49ers +100

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