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MLB lineups for Saturday, April 22: DJ LeMahieu out for Yankees

We provide updates on MLB lineup news, providing fantasy baseball and betting analysis on Saturday, April 22nd.

DJ LeMahieu of the New York Yankees heads back to the dugout against the Los Angeles Angels at Yankee Stadium on April 20, 2023 in the Bronx borough of New York City. The New York Yankees defeated the Los Angeles Angels 9-3. Photo by Elsa/Getty Images

We’ve got a full Saturday slate across MLB, with games running from 1:05 p.m. ET to 9:40 p.m. ET — which means a full day for fantasy baseball managers trying to set their lineups. Luckily, our daily lineup report is here to help with all the latest on who’s sitting and who’s starting around the Majors.

MLB starting lineups: Saturday, April 22

Toronto Blue Jays vs. New York Yankees, 1:05 p.m. ET

Brandon Belt gets another start at DH, while Whit Merrifield will start in left and Santiago Espinal is back at second base for Cavan Biggio.

No DJ LeMahieu for New York today, as Oswald Peraza gets another start at third and Willie Calhoun will DH against Alek Manoah.

Washington Nationals vs. Minnesota Twins, 2:10 p.m. ET

Alex Call is back leading off as Stone Garrett will get a day off against Pablo Lopez.

Byron Buxton moves up to the leadoff spot while Jorge Polanco is back in the lineup again after returning from the IL last night.

Los Angeles Dodgers vs. Chicago Cubs, 2:20 p.m. ET

Mookie Betts will get a start at second base today, as Jason Heyward and David Peralta man the outfield corners and Chris Taylor is back in the lineup at short.

Eric Hosmer is back in the lineup at first base while Tucker Barnhart will spell Yan Gomes behind the plate.

Colorado Rockies vs. Philadelphia Phillies, 3:05 p.m. ET

Charlie Blackmon will lead off as the DH while Ezequiel Tovar is back starting at shortstop. Alan Trejo will handle second base with Yonathan Daza in center.

Encouraging to see Brandon Marsh still starting against a lefty, while Christian Pache and Josh Harrison are in the lineup.

Miami Marlins vs. Cleveland Guardians, Game One, 3:10 p.m. ET

Jazz Chisholm is leading off and playing center in the first game of this doubleheader, while Jorge Soler serves as the DH and Bryan de la Cruz and Avisail Garcia start in the corner outfield spots.

Amed Rosario starts again after missing time with a back ailment while Josh Naylor remains buried at the bottom of the lineup.

Miami Marlins vs. Cleveland Guardians, Game Two, time TBA


New York Mets vs. San Francisco Giants, 4:05 p.m. ET

Chicago White Sox vs. Tampa Bay Rays, 4:05 p.m. ET

The White Sox are stacking righties against Shane McClanahan, with Elvis Andrus leading off, Jake Burger at third and Seby Zavala handling catching duties for Yasmani Grandal.

Taylor Walls and Josh Lowe will start again while Francisco Mejia takes over for Christian Bethancourt behind the dish and Isaac Paredes gets a day off.

Cincinnati Reds vs. Pittsburgh Pirates, 6:35 p.m. ET


Detroit Tigers vs. Baltimore Orioles, 7:05 p.m. ET


Oakland Athletics vs. Texas Rangers, 7:05 p.m. ET


Boston Red Sox vs. Milwaukee Brewers, 7:10 p.m. ET


Houston Astros vs. Atlanta Braves, 7:20 p.m. ET


San Diego Padres vs. Arizona Diamondbacks, 8:10 p.m. ET


Kansas City Royals vs. Los Angeles Angels, 9:07 p.m. ET


St. Louis Cardinals vs. Seattle Mariners, 9:40 p.m. ET