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MLB lineups for Friday, May 19: Vladimir Guerrero Jr., Jose Altuve return

We provide updates on MLB lineup news, providing fantasy baseball and betting analysis on Friday, May 19.

Vladimir Guerrero Jr. of the Toronto Blue Jays looks on from the dugout prior to a game against the New York Yankees at Rogers Centre on May 16, 2023 in Toronto, Ontario, Canada. Photo by Vaughn Ridley/Getty Images

After a light, six-game slate on Thursday, MLB is back with a full night of baseball on Friday, May 19, There are plenty of injury situations to monitor around the league, from Vladimir Guerrero Jr.’s knee to Manny Machado’s hand to Jose Altuve’s season debut, and our daily lineup report will keep you up to date on who’s starting and sitting so you can set your lineups with confidence.

MLB starting lineups: Friday, May 19

Arizona Diamondbacks vs. Pittsburgh Pirates, 6:35 p.m. ET

Ketel Marte returns at second base with Pavin Smith at DH and Dominic Fletcher continuing to hold down center field.

Andrew McCutchen slides up into the leadoff spot with Jack Suwinski starting in center and batting third. Ji-Hwan Bae means second while Josh Palacios takes right as Connor Joe and Rodolfo Castro sit.

New York Yankees vs. Cincinnati Reds, 6:40 p.m. ET

Jake Bauers gets a shot at the leadoff spot with Willie Calhoun serving as the DH and Oswaldo Cabrera at third.

Matt McLain is back at short and will bat second tonight, with Henry Ramos serving as the DH and Jose Barrero manning center with TJ Friedl still out.

Milwaukee Brewers vs. Tampa Bay Rays, 6:40 p.m. ET

Owen Miller leads off again with a lefty on the hill, as Christian Yelich returns from his back injury and Darin Ruf serves as the DH. Mike Brosseau will get a start at first as Rowdy Tellez sits again.

Josh Lowe leads off for the second day in a row while Wander Franco returns to the lineup at short. Still no Yandy Diaz, though, with Luke Raley at first, Taylor Walls at third and Harold Ramirez at DH.

Detroit Tigers vs. Washington Nationals, 7:05 p.m. ET

Zack McKinstry will lead off and start at third with Andy Ibanez at second, Nick Maton at DH and Akil Baddoo in left.

The red-hot Lane Thomas leads off against a lefty while Joey Meneses returns from the paternity list at DH and Stone Garrett gets a start in left.

Chicago Cubs vs. Philadelphia Phillies, 7:05 p.m. ET

A big shake-up for the slumping Cubs, as Nico Hoerner returns atop the lineup while Cody Bellinger goes on the IL and Eric Hosmer gets designated for assignment. Trey Mancini will get the start at first with Christopher Morel in center while Matt Mervis sits.

Business as usual for Philly, with Edmundo Sosa getting a start at third while Alec Bohm slides over to first.

Baltimore Orioles vs. Toronto Blue Jays, 7:07 p.m. ET

Anthony Santander will serve as the DH as Ryan McKenna gets a start in right against a lefty, Joey Ortiz takes third and Gunnar Henderson sits.

Vlad Guerrero Jr. is back after missing a few days with a knee injury. He’ll DH tonight, with Brandon Belt at first and Kevin Kiermaier returning in center.

Cleveland Guardians vs. New York Mets, 7:10 p.m. ET

Jose Ramirez returns from the bereavement list while Josh Naylor will serve as the DH as he battles a leg injury.

Pitchforks down, Mets fans, Mark Vientos is in the lineup tonight. He’ll serve as the DH with Brett Baty at third, Starling Marte back in right and Francisco Alvarez behind the dish.

Seattle Mariners vs. Atlanta Braves, 7:20 p.m. ET

Same old same old for Seattle, with J.P. Crawford leading off, Taylor Trammell at DH and Jose Caballero at second.

Eddie Rosario gets a start in left with the red-hot Marcell Ozuna at DH and Orlando Arcia at short.

Colorado Rockies vs. Texas Rangers, 8:05 p.m. ET

Charlie Blackmon will lead off and serve as the DH with Ryan McMahon at third, Michael Toglia at first and Ezequiel Tovar at short. Randal Grichuk starts in left as Jurickson Profar sits.

Corey Seager returns to shortstop after serving as the DH this week, with Robbie Grossman in left and Ezequiel Duran as the DH tonight.

Oakland Athletics vs. Houston Astros, 8:10 p.m. ET

Ryan Noda starts at first with Shea Langeliers behind the plate and JJ Bleday in left.

Welcome back, Jose Altuve. The All-Star second baseman will lead off in his season debut tonight, with Yordan Alvarez at DH and Corey Julks in center. Mauricio Dubon and Chas McCormick will both sit.

Kansas City Royals vs. Chicago White Sox, 8:10 p.m. ET

Edward Olivares gets a start at DH with Hunter Dozier at third and Jackie Bradley Jr. in center.

Yoan Moncada will start at third with Jake Burger at DH, Gavin Sheets in right and Romy Gonzalez at second as Elvis Andrus and Yasmani Grandal sit.

Los Angeles Dodgers vs. St. Louis Cardinals, 8:15 p.m. ET

No Max Muncy tonight for L.A. against a lefty, as Chris Taylor will play third, J.D. Martinez serves as the DH and Trayce Thompson gets the nod in left.

Nolan Gorman will start at second with Willson Contreras serving as the DH and Brendan Donovan playing left as Tommy Edman gets a day off.

Minnesota Twins vs. Los Angeles Angels, 9:38 p.m. ET

Donovan Solano leads off and starts at first base with a lefty on the mound, with Buck Farmer up to the cleanup spot and Kyle Garlick getting a start in right. Willi Castro starts at second for the injured Jorge Polanco while Joey Gallo (leg) also sits.

It’ll be a rest day for Mike Trout, as Mickey Moniak leads off and starts in center with Taylor Ward in left and Brandon Drury at first.

Boston Red Sox vs. San Diego Padres, 9:40 p.m. ET

Rob Refsnyder will start in left and bat third against lefty Blake Snell, with Enrique Hernandez at short, Justin Turner at first, Masataka Yoshida in left and Denyi Reyes at second.

Manny Machado is out again as he nurses a fracture in his hand, as Ha-Seong Kim slides over to third, Jake Cronenworth takes second and Brandon Dixon starts at first. Nelson Cruz will serve as the DH against a lefty.

Miami Marlins vs. San Francisco Giants, 10:15 p.m. ET

Jean Segura leads off again with Garrett Hampson manning center in lieu of Jazz Chisholm, flanked by the red-hot Bryan de la Cruz in left and Peyton Burdick in right.

LaMonte Wade Jr. leads off again with Michael Conforto, Mike Yastrzemski and Mitch Haniger comprising the outfield, J.D. Davis at DH and Blake Sabol behind the plate.