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Cardinals vs. 49ers inactives: Who is not playing in Week 18

The Cardinals and 49ers meet in Week 18 of the NFL season. We break down what we know before Week 18 inactives arrive at 2:55 p.m. ET on Sunday.

Wide receiver DeAndre Hopkins #10 of the Arizona Cardinals during the NFL game at State Farm Stadium on December 12, 2022 in Glendale, Arizona. Photo by Christian Petersen/Getty Images

Cardinals-49ers inactives

Cardinals: RB James Conner, WR DeAndre Hopkins, QB Colt McCoy, LB Zaven Collins, CB Marco Wilson, CB Antonio Hamilton, OL Lecitus Smith, WR Robbie Anderson, DL Zach Allen

49ers: QB Jimmy Garoppolo, TE Ross Dwelley, G Aaron Banks, LB Dre Greenlaw, DE Drake Jackson, DT Kevin Givens, CB Ambry Thomas


The Arizona Cardinals and San Francisco 49ers face off in Week 18 to close out the 2022-23 NFL regular season. The 49ers are in the playoffs but can still improve their seeding with a win and an Eagles loss. The Cardinals are sitting in the No. 4 draft position and could climb as high as No. 2 depending on how the Bears and Broncos do on Sunday. San Francisco is a 14-point favorite at DraftKings Sportsbook.

We don’t have the official inactives report yet as it is released an hour and a half before kickoff, but we know which players are definitely not playing. The Cardinals have ruled out a sizable number of players, including DE Zach Allen (hand), WR Robby Anderson (back), LB Zaven Collins (calf), RB James Conner (knee, shin), CB Antonio Hamilton (hip), WR DeAndre Hopkins (knee), QB Colt McCoy (concussion), and CB Marco Wilson (neck). The 49ers have ruled out G Aaron Banks (ankle, knee), QB Jimmy Garoppolo (foot), DT Kevin Givens (knee), LB Dre Greenlaw (back), and CB Ambry Thomas (ankle).

We will get the full list of inactives around 2:55 p.m. ET, but for now, here is what we know about players in question.

The Cardinals have designated LB Victor Dimukeje (illness), DT Leki Fotu (shoulder), CB Josh Jackson (hamstring), and LB Tanner Vallejo (knee, wrist) as questionable. The 49ers have designated DT Arik Armstead (foot, ankle) and DT Javon Kinlaw (illness, knee) as questionable. Deebo Samuel came off the injury report and Elijah Mitchell was activated off IR for the game.