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The New York Giants travel to San Francisco this week to take on the 49ers. The 49ers are coming off a solid 31-13 win over the Jets in week two. The win helped the 49ers get back to 1-1 on the year, but the numbers of injuries that hit Kyle Shanahan’s team left them reeling.
The Giants lost Saquon Barkley for the season to a brutal ACL tear in their loss to the Bears. New York is 0-2 on the season and desperate for something hopeful in their matchup with the 49ers.
Both teams have very different goals for the season, but both come into this week already depleted after two weeks of play. Each need some level of injury luck this week as they try to adapt to their respective new normals.
TV Info
Date: Sunday, September 27
Time: 1 p.m. ET
Channel: FOX
Broadcast map
Notable Statistical rankings (Football Outsiders)
49ers: 14th vs. Pass, 8th vs. Rush
Giants: 12th vs. Pass, 6th vs. Rush
DraftKings Sportsbook odds
49ers: -4, -195
Giants: +4, +165
Total: 41.5
Injury report
49ers
OUT: RB Tevin Coleman (knee), DE Dee Ford (back), QB Jimmy Garoppolo (ankle), LB Dre Greenlaw (quadricep), TE George Kittle (knee), RB Raheem Mostert (knee)
QUESTIONABLE: CB Ahkello Witherspoon (hamstring)
Giants
DOUBTFUL: S Adrian Colbert (quadricep)
QUESTIONABLE: CB Brandon Williams (groin)
Fantasy football start/sit advice
49ers
Nick Mullens, Quarterback, $5,100
You might be tempted to throw Nick Mullens a start this week. Don’t give in. Mullens is the assumed starter with Jimmy Garoppolo out with an ankle injury. Seeing how comfortable Mullens is with a quickly shifting 49ers offense is key, and you don’t want your fantasy team relying on it.
Giants
Dion Lewis, Running Back, $5,300
With the glaring absence of Saquon Barkley in the Giants backfield this week, Dion Lewis and Wayne Gallman will be the two competing for touches. Lewis feels like the man this week against a more vulnerable and injury riddled 49ers defense.
Giants, Defense, $2,700
Of all the weeks to get value out of the Giants defense, it’s this week. The 49ers are beat up and disheveled, ready to put up a dud of an offensive performance. The Giants did a solid job against the Bears and Steelers defensively in the first two weeks of the season, enough to justify a start.