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Here’s the Colts full schedule for the 2021 NFL Season

The NFL released the Indianapolis Colts schedule on Wednesday, May 12. We break it down, including a full list of games, prime time matchups, and strength of schedule.

Michael Pittman #11 of the Indianapolis Colts takes the field prior to an AFC Wild Card playoff game against the Buffalo Bills at Bills Stadium on January 09, 2021 in Orchard Park, New York. Photo by Bryan Bennett/Getty Images

The NFL announced the complete 2021 schedule on Wednesday, May 12, and the Indianapolis Colts are officially set to kick off their 2021 season at home against the Seattle Seahawks at 1 PM. Their first divisional game will be in Week 3 against the Tennessee Titans on the road.

The Colts finished the 2020 season with an 11-5 record, tied for the best mark in the AFC South, and they fell to the Buffalo Bills in the wild card round. Indianapolis will have a much different look this as Phillip Rivers announced his retirement after one season with the Colts. Carson Wentz is going to be the Indianapolis quarterback this season as he is reunited with Frank Reich after a trade with the Philadelphia Eagles. The Colts tried to improve the defense in the draft where they selected a pair of defensive ends with their first two picks. If Wentz can improve his play from the past few seasons with the new change of scenery, the Colts could be the favorites to claim the division.

All times listed are Eastern.

Odds

Win total, over/under: O 10 (+110), U 10 (-134)
Division champs: -106

Prime time games

Week 5: Oct. 11 at Baltimore Ravens (MNF) 8:15 PM ESPN
Week 7: Oct. 24 at San Francisco 49ers (SNF) 8:20 PM NBC
Week 9: Nov. 4 New York Jets (TNF) 8:20 PM FOX/NFLN/Amazon
Week 16: Dec. 25 at Arizona Cardinals (Christmas) 8:15 PM NFLN

Strength of schedule

Super Bowl odds: 13th
2021 win totals: 14th
2020 records: 9th

2021 Schedule

Week 1: Sep. 12 Seattle Seahawks 1:00 PM FOX
Week 2: Sep. 19 Los Angeles Rams 1:00 PM FOX
Week 3: Sep. 26 at Tennessee Titans 1:00 PM CBS
Week 4: Oct. 3 at Miami Dolphins 1:00 PM CBS
Week 5: Oct. 11 at Baltimore Ravens (Mon) 8:15 PM ESPN
Week 6: Oct. 17 Houston Texans 1:00 PM CBS
Week 7: Oct. 24 at San Francisco 49ers 8:20 PM NBC*
Week 8: Oct. 31 Tennessee Titans 1:00 PM CBS
Week 9: Nov. 4 New York Jets (Thu) 8:20 PM FOX/NFLN/Amazon**
Week 10: Nov. 14 Jacksonville Jaguars 1:00 PM CBS
Week 11: Nov. 21 at Buffalo Bills 1:00 PM CBS
Week 12: Nov. 28 Tampa Bay Buccaneers 1:00 PM FOX
Week 13: Dec. 5 at Houston Texans 1:00 PM CBS
Week 14: BYE
Week 15: Dec. 18 or 19 (Sat/Sun) New England Patriots TBD
Week 16: Dec. 25 at Arizona Cardinals 8:15 PM NFLN
Week 17: Jan. 2 Las Vegas Raiders 1:00 PM CBS
Week 18: Jan. 9 at Jacksonville Jaguars 1:00 PM CBS

* - Sunday night games in Weeks 5-17 subject to change; Week 18 game TBD
**NFL Network and Amazon simulcast subject to change