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NFL Week 10 Underdog Picks: Football Predictions, Bets to Consider on DraftKings Sportsbook

Mike Barner gives his top NFL underdog bets to consider on DraftKings Sportsbook for Week 10.

The Giants were the only underdog to come through for me in Week 9, leaving me with a 1-2 record. For the season, I’m now 12-14-1 with my underdog picks. Let’s try to get back over .500 with three more wagers to consider in Week 10. All odds were obtained from DraftKings Sportsbook.

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Carolina Panthers vs. Tampa Bay Buccaneers: Panthers +6

Talk about an embarrassing loss. The Bucs were steamrolled by the Saints on Sunday, losing 38-3. They have only lost three games all season, but two of them have come against the Saints. They were actually lucky to come away with a two-point win the week prior against the Giants, considering how poorly they played in the first half. All of that being said, they are still an extremely dangerous team that has posted impressive wins over the Packers and Raiders.

One of the Bucs’ wins this season came against the Panthers, who they defeated by 14 points in Week 2. The Panthers went on a three-game winning streak after the loss, but followed that run up by losing each of their last four contests. On the bright side, two of those losses came by three or fewer points, including a two-point defeat at the hands of the Chiefs last week. Losing Christian McCaffrey (shoulder) again is a tough blow, but they still have Mike Davis and have played in a lot of close games, so I’ll take a chance on the points here.


Cincinnati Bengals at Pittsburgh Steelers: Bengals +7

Both of these teams enter Week 10 dealing with COVID-19 complications. The Steelers have maybe the most concerning case in terms of the possible impact on this game with Ben Roethlisberger having been placed on the Reserve/COVID-19 list. The good news is he didn’t test positive, he was only considered a close contact of Vance McDonald, who did test positive. As long as Roethlisberger continues to return negative tests, he can be activated in time for this matchup.

On the surface, this seems like an epic mismatch based on these two team’s records. However, the Steelers haven’t been blowing away their opponents lately, winning each of their last three games by five or fewer points. That included a five-point win over the Cowboys last week, who were starting their fourth-string quarterback. Meanwhile, the Bengals defeated the Titans in their last game before their bye, and four of their five losses this season have come by five points or fewer. It wouldn’t be a surprise to see them keep this close.


Buffalo Bills at Arizona Cardinals: Bills +2.5

Yes, two of the Bills’ wins this season have come against the lowly Jets. However, they also have some signature wins over the Rams, Raiders and Seahawks. Their only two losses have come against the Titans and Chiefs, so they certainly haven’t fallen to any inferior foes. Their offense has been the main reason for their success considering they have scored at least 30 points in four of their seven wins.

The Cardinals had their three-game winning streak snapped last week when they fell to the Dolphins by three points at home. It’s worth noting that while the Cardinals are 5-3, two of their three losses have come at home. One of them wasn’t exactly against an overwhelming team in the Lions, either. This should be a high-scoring game with how well both Josh Allen and Kyler Murray are playing. I could see it going either way, so not only would I consider taking the Bills at +2, but throwing some cash on the Bills’ moneyline (+120) may even be worth it.

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All betting odds provided by DraftKings Sportsbook and all odds subject to change.


I am a promoter at DraftKings and am also an avid fan and user (my username is mbarner51) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.


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