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NFL Week 3 Underdog Picks: Football Predictions, Bets to Consider on DraftKings Sportsbook

Mike Barner gives his top NFL underdog bets to consider on DraftKings Sportsbook for Week 3.

Coming off of a successful 2-1 set of picks in Week 2, the column now has a record of 3-2-1 through the first two weeks. If you’re looking to take a chance on some more underdogs in Week 3, here are three that could turn out to be profitable.

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New York Giants vs. San Francisco 49ers: Giants +4

This Giants suffered arguably the biggest injury across the league in Week 2, when they lost star running back Saquon Barkley (knee) for the season. There is no one who can replace him, but the Giants did quickly add to their depth at the position by signing Devonta Freeman. They’ll also have to deal with a key injury at wide receiver since Sterling Shepard (toe) was placed on IR. That should leave Darius Slayton, Golden Tate and Evan Engram very busy moving forward, especially as they try to ease Freeman into their offensive system.

As bad as things are for the Giants, it’s even worse for the 49ers. Players who have either already been ruled out or are unlikely to play in this game include Raheem Mostert (knee), Tevin Coleman (knee), Jimmy Garoppolo (ankle), Deebo Samuel (foot), Nick Bosa (knee), Solomon Thomas (knee) and Richard Sherman (calf). With so many injuries to key components on both sides of the ball, the Giants can keep this game close despite losing some players of their own. Frankly, it wouldn’t be shocking to see the Giants win this game on their home field.

See more betting information for the New York Giants and San Francisco 49ers at the DraftKings Sportsbook NFL team odds page.


Cincinnati Bengals at Philadelphia Eagles: Bengals +4.5

Things are not looking good for the Eagles right now. They sit at 0-2 after a blowout loss to the Rams and a shocking loss at the hands of Washington in Week 1. Their offense has looked out of sync and that likely won’t improve much this week with wide receiver Jalen Reagor (thumb) now on the shelf. With little depth behind DeSean Jackson, they will have to rely even more on their two talented tight ends: Zach Ertz and Dallas Goedert.

The Bengals are also 0-2, but their record has an entirely different feel to it. Both of their losses have come by five points or fewer and they are largely healthy on offense outside of tight end C.J Uzomah (Achilles). Rookie quarterback Joe Burrow looked outstanding against the Browns in Week 2, throwing for 316 yards and three touchdowns. The Bengals have a lot of talent on offense, so I expect them to make this one difficult for the Eagles.


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Detroit Lions at Arizona Cardinals: Lions +5.5

On the surface, this might not look like a good underdog to take a chance on. The Cardinals have stormed out to a 2-0 record and the Lions sit at 0-2. However, the Lions should have won against the Bears in Week 1, but their defense blew a big lead in the fourth quarter. They have also played their first two games without Kenny Golladay (hamstring), who could make his return in this contest. Adding him back would completely change the outlook of their offense. Marvin Jones is an excellent second option in the passing game, but he’s not equipped to be a team’s top receiving option at this stage of his career.

Make no mistake about it, the Cardinals defeat of 49ers to open the season was impressive. They followed that up with a 15-point win over a far inferior foe in Washington, who couldn’t slow down Kyler Murray. The Lions will likely have similar difficulties, but their offense could take a significant leap forward if Golladay does return, which could enable them to keep this close.

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I am a promoter at DraftKings and am also an avid fan and user (my username is mbarner51) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.


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