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Madden Stream Picks: Top DraftKings Fantasy Football DFS Targets, Values for September 25

Zach Thompson gives his top studs and value plays at each position for Friday’s three-game Madden Stream DraftKings slate, which starts at 6:00 p.m. ET.

Celebrate Friday on the DraftKings Dream Stream with six more Madden 21 matchups scheduled throughout the day. Each matchup has single-game Showdown contests available, and there are also a pair of three-game classic slates kicking off at 12 p.m. ET and 6 p.m. ET. The second of those classic slates is the featured slate of the day and also the focus of this post. The action for this slate starts at 6 p.m. ET with a preview of the Sunday Night Football matchup this weekend between the Packers and the Saints. In primetime, the Chiefs will host the 49ers at 8 p.m. ET, and in the final game of the night the Patriots welcome in the Ravens on Madden After Dark.

The roster for each team has been updated to include player movement before Week 1 of this season, so make sure to take a look at the new depth charts, abilities and X-factors for Madden 21 along with the upcoming schedule on the Madden Stream info page. The rosters have also been adjusted to get the best players on the field and will not be impacted by any COVID-19 opt-outs or injuries.

Check out the daily DraftKings Madden Stream contests lobby with paid contests for real cash prizes now available alongside free contests. Each simulation will be played out computer vs. computer via an online Madden Stream using Madden 21. In this format, you can enjoy watching the game stream on the DraftKings YouTube channel, the DK Live app (download here) or right here in this post.

Set your DraftKings lineups here: Madden Stream $4K Friday Night Special [$1K to 1st] and your FREE lineups here: Madden Stream $500 FREE Contest.

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Patrick Mahomes, Kansas City Chiefs vs. San Francisco 49ers, $7,400 — Two of the best QBs in all of our sims lead the way on this slate’s salary list. While Lamar Jackson ($7,900) offers immense upside and can be a beast in these sims, he has been a little inconsistent lately and hasn’t shown quite the ceiling that Mahomes has flashed. In his 10 sims in Madden 21, Mahomes is averaging 22.0 DKFP and has produced over 20 DKFP in half of those contests. He has also reached over 34 DFKP in two of those contests, while Jackson has yet to post more than 29 DKFP in any of his Madden 21 sims. Mahomes has thrown 18 touchdowns and run for three more while averaging an impressive 277.3 passing yards per sim. Even though the 49ers are a solid defense, I think Mahomes is the better play on this slate, and he even comes a little bit cheaper than Jackson.

Other Option — Lamar Jackson ($7,900)


Aaron Rodgers, Green Bay Packers at New Orleans Saints, $6,500 — If you’re not playing one of the members of the $7K club, Rodgers is the best of the other four options. He has thrown for exactly two touchdowns in seven straight sims with over 20 DKFP in five of those seven contests. Rodgers threw for 370 yards and two touchdowns against the 49ers in his most recent sim, posting a very impressive 28.6 DKFP. His ceiling isn’t quite as high as Mahomes’ can be, but he still has plenty of potential in what could be a high-scoring contest in the Superdome.

Other Options — Drew Brees ($6,100), Jimmy Garoppolo ($5,300)

Running Back


Raheem Mostert, San Francisco 49ers at Kansas City Chiefs, $7,300 — Mostert is dealing with an injury in real life, but he’ll be healthy and ready to carry the load for the 49ers in this sim. He typically gets a very heavy workload as the RB1, power back and third-down back, allowing him to pile up nine touchdowns in San Francisco’s eight sims. Mostert has over 19 DKFP in four straight sims and showed off an immensely high ceiling with 39.0 DKFP against the Ravens a few sims ago. Since the 49ers will be trying to keep the time of possession slanted their way to keep the ball away from Mahomes, Mostert should once again be the focus of their offense in this matchup.

Other Options — Alvin Kamara ($8,100), Aaron Jones ($6,700)


J.K. Dobbins, Baltimore Ravens at New England Patriots, $3,800 — Dobbins serves as the Ravens’ third-down and power back in our most recent roster update and has turned those roles into some solid production. He had a touchdowns and 12.2 DKFP in his Madden sim debut against the Packers, and then he followed that up with four catches for 26 yards on his way to 7.0 DKFP against the Saints in his most recent sim. At under $4K, he gives you the flexibility to spend big at other spots and should be involved either as a rusher, a receiver or both against the Patriots.

Other Options — Sony Michel ($4,500), James White ($4,200)

Wide Receiver


Tyreek Hill, Kansas City Chiefs vs. San Francisco 49ers, $7,500 — Hill has been excellent in his 10 sims in Madden 21, averaging 6.4 catches for 86.3 yards per contest and scoring a total of seven touchdowns. His 99 speed rating continues to make him a big-play threat in every contest and his volume makes him the best WR to pay up for on this slate. He has over 22 DKFP in five of his 10 sims and is averaging a very impressive 20.2 DKFP per contest. San Francisco typically does not move Richard Sherman into the slot, which would leave Hill in a very favorable matchup against one of the 49ers’ other CBs.

Other Options — Davante Adams ($6,900), Devin Funchess ($6,300)


Marquise Brown, Baltimore Ravens at New England Patriots, $4,900 — Brown has been inconsistent due to the lack of volume available sometimes in the Ravens’ passing game, but he has also shown nice upside due to his big-play potential with his 97 speed rating. Coming into his most recent contest, Brown had found the end zone in two straight sims with 15.5 DKFP against the Packers and 25.9 DKFP against the 49ers. However, he was totally shut out of the Ravens’ game against the Saints, showing he remains a boom-or-bust play with a high ceiling.

Marquez Valdes-Scantling, Green Bay Packers at New Orleans Saints, $3,100 — With so many high-priced options in play, you’ll need to go cheap in some spots, and MVS is a great play even though he costs barely over the minimum salary. He is in place as the Packers’ slot receiver and WR3 and has lots of potential in that role due to his 93 speed rating and 85 catching rating. The Saints have been beatable out of the slot, and MVS is usually good for at least a few catches. Even if he doesn’t go off for a huge game, he should be able to offer solid returns at his affordable salary while allowing you to target top options elsewhere.

Other Options — N’Keal Harry ($4,300), Kendrick Bourne ($4,100)

Tight End


Travis Kelce, Kansas City Chiefs vs. San Francisco 49ers, $6,600 — It’s amazing how both Kelce and Hill continue to get such high volume for the Chiefs. Kelce is averaging an amazing 7.1 catches per contest and has at least five catches in each of his past nine games. He has found the end zone six times in his 10 sims in Madden 21 including five times in his past six contests. He has over 18 DKFP in seven of his past eight games and brings both low risk and a high ceiling due to his consistently heavy workload.

Other Options— George Kittle ($5,800), Jared Cook ($4,700)


Devin Asiasi, New England Patriots vs. Baltimore Ravens, $4,400 — The rookie hasn’t been very involved in the offense yet in the real world, but he is already a nice option in simland, averaging 4.6 catches for 48.2 yards per sim. He hasn’t come close to matching Kelce’s volume but does have a good route tree in New England’s playbook and usually gets attention from Cam Newton ($6,000), who likes to rely on his TE. If you can’t afford Kelce or are looking to go with two TEs, Asasi is a solid affordable pivot.

Other Option— Mark Andrews ($3,600)



Ravens DST at New England Patriots, $3,000 — With very good offenses across the board on this slate, the Patriots are actually one of the better matchups available. The Ravens have also been doing great work on defense in their Madden 21 sims, getting excellent play from Calais Campbell up front. The unit has stacked up 21 sacks in just seven sims while scoring a defensive touchdown as well. They have never allowed more than 26 points in any sim and have held their opponent to 17 points or fewer in five of their seven contests.


Chiefs DST vs. San Francisco 49ers, $2,700 — While Mostert has made the 49ers decent on offense, they still struggle to pass the ball effectively. The Chiefs’ DST should be able to get pressure on Jimmy G and could force turnovers, especially if they get out to an early lead and force the 49ers go pass-heavy. Kansas City has picked up 19 sacks in 10 sims and also forced six turnovers. With a pair of defensive touchdowns as well, they are averaging a solid 6.4 DKFP per contest and have reached double-digit DKFP three times, showing they have a nice ceiling.

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I am a promoter at DraftKings and am also an avid fan and user (my username is Z.Thompson) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.