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MLB Best Bets: Baseball Picks, Predictions, Odds to Consider on DraftKings Sportsbook for May 22

Kenny Ducey gives his best bets on DraftKings Sportsbook for Saturday’s MLB betting card.

MLB: Tampa Bay Rays at Baltimore Orioles Tommy Gilligan-USA TODAY Sports

Congratulations, we’ve made it to the weekend. As a reward, we’ve got a splendid slate on the diamond to choose from with every team in action. I’ve got my eye on quite a few bets today, but have narrowed it down to three. With that in mind, here are my best MLB bets to consider on DraftKings Sportsbook.



Chicago Cubs at St. Louis Cardinals

Cardinals ML -104

After fighting hard against the Cubs but seeing their efforts crushed by their bullpen, I think the Cardinals’ lineup should come back with a vengeance on Saturday against their division rivals. Adbert Alzolay has some nice strikeout and walk numbers, but has yet to impress me this season and also hasn’t held a club under two runs thus far. His 41.5% hard-hit rate should be his undoing against a Cardinals offense that makes quality contact, allowing the Redbirds should prevail. The Cubs have lived on contact lately, and haven’t walked or hit for power, which should play right into Miles Mikolas’ hands. The righty returns from his long injury absence today and has always been a master of limiting walks and inducing soft contact. Without the Cubs’ power bats posing a real threat, he should be able to navigate Chicago’s lineup with ease.


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Tampa Bay Rays at Toronto Blue Jays

Rays First Five Innings +102

Yeah, look ... Robbie Ray? He’s just not doing it for me. I don’t believe one bit that this guy is any different than the pitcher we’ve seen for years now, who has been absolutely lit up by opposing offenses. He’s allowing hard contact at nearly a 50% clip, which is more than enough to cancel out his solid strikeout-to-walk ratio. I will take the offense that is slightly worse against lefties facing Ray over the one that’s better, which has to face the flame-throwing Shane McClanahan. He’s been even more elite in the strikeout category than Ray, which should play up against a team full of “Three True Outcome” guys.


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Oakland Athletics at Los Angeles Angels

A’s ML -136

The Oakland offense has been on a roll lately, posting a 118 wRC+ over the past two weeks to rank just outside the top five in baseball. Even bats like Elvis Andrus have gotten in on the fun, making this a near-impossible task for a pitcher to accomplish. Unfortunately for the Halos, Patrick Sandoval and his 5.56 ERA are not the answer here against the A’s.

On the other hand, Chris Bassitt has gone from auto-fade to shover, posting a respectable 3.45 xERA. With a clear edge on both sides of the ball, I think the A’s should be more like -150 favorites here, even on the road.

Place your MLB bets at DraftKings Sportsbook and bet online by downloading the DraftKings Sportsbook app.


All odds provided by DraftKings Sportsbook and all odds subject to change.


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I am a promoter at DraftKings and am also an avid fan and user (my username is jetsfan196) and I may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.