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First Look NFL 2021 Week 1 DraftKings Fantasy Football Picks

Pat Mayo goes position-by-position breaking down the Week 1 Sunday NFL slate, giving his DraftKings picks for GPPs.

Pat Mayo and Chris Meaney go position-by-position, providing their FIRST LOOK at the newly released Week 1 DraftKings NFL Sunday main slate, giving their 2021 Week 1 DraftKings picks for DraftKings GPPs.

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2021 Top 150 RANKINGS — 1-50 | 51-100 | RB Ranks | RB Tiers | List

Week 1 DraftKings — First Look | STACKS | RB | WR | QB | TE | DK Tools

Player Props — Cowboys | Jets | Chargers | Best Ball Strategy

NFL Strategy Michael Thomas Injury | 2021 Projections | Advanced Stats

How To Bet on NFL Guide + Strategy | Podcast | For Beginners | Gambling Myths

Podcasts — YouTube | Apple | Spotify | Insta | Google | Twitter | E-Mail

First Look 2021 Week 1 DraftKings Picks Position Index

Week 1 DraftKings Cheap Lineup Stacks
Week 1 DraftKings Running Backs & Values
Week 1 DraftKings Wide Receivers & Values
Week 1 DraftKings Quarterbacks & Values
Week 1 DraftKings Tight Ends & Values
Week 1 DraftKings DST & Values

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For sports betting, head over to DraftKings Sportsbook or download the DraftKings Sportsbook app.

Pat Mayo is an award-winning video host and producer of long and short-form content, and the host of The Pat Mayo Experience daily talk show. (Subscribe for video or audio). Mayo (@ThePME) won the 2020 Fantasy Sports Writing Association Daily Fantasy Writer of the Year and Golf Writer of the Year awards, along with the Fantasy Sports Trade Association Best Sports Betting Analyst award, and was finalist for four FSWA Awards in 2020 (Best Podcast, Best Video, Daily Fantasy Writer of the Year, Golf Writer of the Year). His 21 FSWA nominations lead all writers this decade and are third-most all-time. Mayo has been recognized across multiple sports (Football, Baseball & Golf), mediums (Video, Writing & Podcasting), genre (Humor), and game formats (Daily Fantasy and Traditions Season Long). Beyond sports, Mayo covers everything from entertainment to pop culture to politics. If you have a fantasy question, general inquiry or snarky comment, ship it to Mayo at and the best will be addressed on the show.

I am a promoter at DraftKings and am also an avid fan and user (my username is ThePME) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.

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